SEARCH OUR PRODUCT CATALOG

SAE1-WDR18 Fusion FISH Probe

The SAE1-WDR18 Fusion FISH Probe is used to confirm a fusion of the SAE1 and WDR18 genes. The fusion of the SAE1 and WDR18 genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
SAE1-WDR18-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
SAE1-WDR18-20-RERE 20 (40 μL) 200 μL
SAE1-WDR18-20-REOR 20 (40 μL) 200 μL
SAE1-WDR18-20-REGO 20 (40 μL) 200 μL
SAE1-WDR18-20-REGR 20 (40 μL) 200 μL
SAE1-WDR18-20-REAQ 20 (40 μL) 200 μL
SAE1-WDR18-20-ORRE 20 (40 μL) 200 μL
SAE1-WDR18-20-OROR 20 (40 μL) 200 μL
SAE1-WDR18-20-ORGO 20 (40 μL) 200 μL
SAE1-WDR18-20-ORAQ 20 (40 μL) 200 μL
SAE1-WDR18-20-GORE 20 (40 μL) 200 μL
SAE1-WDR18-20-GOOR 20 (40 μL) 200 μL
SAE1-WDR18-20-GOGO 20 (40 μL) 200 μL
SAE1-WDR18-20-GOGR 20 (40 μL) 200 μL
SAE1-WDR18-20-GOAQ 20 (40 μL) 200 μL
SAE1-WDR18-20-GRRE 20 (40 μL) 200 μL
SAE1-WDR18-20-GROR 20 (40 μL) 200 μL
SAE1-WDR18-20-GRGO 20 (40 μL) 200 μL
SAE1-WDR18-20-GRGR 20 (40 μL) 200 μL
SAE1-WDR18-20-GRAQ 20 (40 μL) 200 μL
SAE1-WDR18-20-AQRE 20 (40 μL) 200 μL
SAE1-WDR18-20-AQOR 20 (40 μL) 200 μL
SAE1-WDR18-20-AQGO 20 (40 μL) 200 μL
SAE1-WDR18-20-AQGR 20 (40 μL) 200 μL
SAE1-WDR18-20-AQAQ 20 (40 μL) 200 μL

SAE1 Gene Summary

Posttranslational modification of proteins by the addition of the small protein SUMO (see SUMO1; MIM 601912), or sumoylation, regulates protein structure and intracellular localization. SAE1 and UBA2 (MIM 613295) form a heterodimer that functions as a SUMO-activating enzyme for the sumoylation of proteins (Okuma et al., 1999 [PubMed 9920803]).[supplied by OMIM, Mar 2010]

Gene Name: SUMO1 Activating Enzyme Subunit 1

Chromosome: CHR19: 47634079 -47713893

Locus: 19q13.32

WDR18 Gene Summary

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. [provided by RefSeq, Jul 2008]

Gene Name: WD Repeat Domain 18

Chromosome: CHR19: 984327 -994569

Locus: 19p13.3

Gene Diseases

The SAE1 WDR18 Fusion has been associated with the following diseases:

Disease Name
Kidney Renal Clear Cell Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.