SAFB2-KHSRP Fusion FISH Probe
The SAFB2-KHSRP Fusion FISH Probe is used to confirm a fusion of the SAFB2 and KHSRP genes. The fusion of the SAFB2 and KHSRP genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SAFB2-KHSRP-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SAFB2-KHSRP-20-RERE | 20 (40 μL) | 200 μL |
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| SAFB2-KHSRP-20-REOR | 20 (40 μL) | 200 μL |
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| SAFB2-KHSRP-20-REGO | 20 (40 μL) | 200 μL |
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| SAFB2-KHSRP-20-REGR | 20 (40 μL) | 200 μL |
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| SAFB2-KHSRP-20-REAQ | 20 (40 μL) | 200 μL |
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| SAFB2-KHSRP-20-ORRE | 20 (40 μL) | 200 μL |
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| SAFB2-KHSRP-20-OROR | 20 (40 μL) | 200 μL |
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| SAFB2-KHSRP-20-ORGO | 20 (40 μL) | 200 μL |
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| SAFB2-KHSRP-20-ORAQ | 20 (40 μL) | 200 μL |
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| SAFB2-KHSRP-20-GORE | 20 (40 μL) | 200 μL |
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| SAFB2-KHSRP-20-GOOR | 20 (40 μL) | 200 μL |
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| SAFB2-KHSRP-20-GOGO | 20 (40 μL) | 200 μL |
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| SAFB2-KHSRP-20-GOGR | 20 (40 μL) | 200 μL |
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| SAFB2-KHSRP-20-GOAQ | 20 (40 μL) | 200 μL |
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| SAFB2-KHSRP-20-GRRE | 20 (40 μL) | 200 μL |
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| SAFB2-KHSRP-20-GROR | 20 (40 μL) | 200 μL |
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| SAFB2-KHSRP-20-GRGO | 20 (40 μL) | 200 μL |
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| SAFB2-KHSRP-20-GRGR | 20 (40 μL) | 200 μL |
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| SAFB2-KHSRP-20-GRAQ | 20 (40 μL) | 200 μL |
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| SAFB2-KHSRP-20-AQRE | 20 (40 μL) | 200 μL |
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| SAFB2-KHSRP-20-AQOR | 20 (40 μL) | 200 μL |
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| SAFB2-KHSRP-20-AQGO | 20 (40 μL) | 200 μL |
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| SAFB2-KHSRP-20-AQGR | 20 (40 μL) | 200 μL |
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| SAFB2-KHSRP-20-AQAQ | 20 (40 μL) | 200 μL |
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KHSRP Gene Summary
The KHSRP gene encodes a multifunctional RNA-binding protein implicated in a variety of cellular processes, including transcription, alternative pre-mRNA splicing, and mRNA localization (Min et al., 1997 [PubMed 9136930]; Gherzi et al., 2004 [PubMed 15175153]).[supplied by OMIM, Apr 2010]
Gene Name: KH-type Splicing Regulatory Protein
Chromosome: CHR19: 6413118 -6424822
Locus: 19p13.3
SAFB2 Gene Summary
The protein encoded by this gene, along with its paralog (scaffold attachment factor B1), is a repressor of estrogen receptor alpha. The encoded protein binds scaffold/matrix attachment region (S/MAR) DNA and is involved in cell cycle regulation, apoptosis, differentiation, the stress response, and regulation of immune genes. [provided by RefSeq, May 2016]
Gene Name: Scaffold Attachment Factor B2
Chromosome: CHR19: 5587009 -5622938
Locus: 19p13.3
Gene Diseases
The SAFB2 KHSRP Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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