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SAMD4B-SPTBN4 Fusion FISH Probe

The SAMD4B-SPTBN4 Fusion FISH Probe is used to confirm a fusion of the SAMD4B and SPTBN4 genes. The fusion of the SAMD4B and SPTBN4 genes has been associated with Colon Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
SAMD4B-SPTBN4-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
SAMD4B-SPTBN4-20-RERE 20 (40 μL) 200 μL
SAMD4B-SPTBN4-20-REOR 20 (40 μL) 200 μL
SAMD4B-SPTBN4-20-REGO 20 (40 μL) 200 μL
SAMD4B-SPTBN4-20-REGR 20 (40 μL) 200 μL
SAMD4B-SPTBN4-20-REAQ 20 (40 μL) 200 μL
SAMD4B-SPTBN4-20-ORRE 20 (40 μL) 200 μL
SAMD4B-SPTBN4-20-OROR 20 (40 μL) 200 μL
SAMD4B-SPTBN4-20-ORGO 20 (40 μL) 200 μL
SAMD4B-SPTBN4-20-ORAQ 20 (40 μL) 200 μL
SAMD4B-SPTBN4-20-GORE 20 (40 μL) 200 μL
SAMD4B-SPTBN4-20-GOOR 20 (40 μL) 200 μL
SAMD4B-SPTBN4-20-GOGO 20 (40 μL) 200 μL
SAMD4B-SPTBN4-20-GOGR 20 (40 μL) 200 μL
SAMD4B-SPTBN4-20-GOAQ 20 (40 μL) 200 μL
SAMD4B-SPTBN4-20-GRRE 20 (40 μL) 200 μL
SAMD4B-SPTBN4-20-GROR 20 (40 μL) 200 μL
SAMD4B-SPTBN4-20-GRGO 20 (40 μL) 200 μL
SAMD4B-SPTBN4-20-GRGR 20 (40 μL) 200 μL
SAMD4B-SPTBN4-20-GRAQ 20 (40 μL) 200 μL
SAMD4B-SPTBN4-20-AQRE 20 (40 μL) 200 μL
SAMD4B-SPTBN4-20-AQOR 20 (40 μL) 200 μL
SAMD4B-SPTBN4-20-AQGO 20 (40 μL) 200 μL
SAMD4B-SPTBN4-20-AQGR 20 (40 μL) 200 μL
SAMD4B-SPTBN4-20-AQAQ 20 (40 μL) 200 μL

SAMD4B Gene Summary

The Sterile Alpha Motif Domain Containing 4B (SAMD4B) gene is located on chr19 :39833107-39875537 at 19q13.2.

Gene Name: Sterile Alpha Motif Domain Containing 4B

Chromosome: CHR19: 39833107 -39875537

Locus: 19q13.2

SPTBN4 Gene Summary

Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. It is composed of two antiparallel dimers of alpha- and beta- subunits. This gene is one member of a family of beta-spectrin genes. The encoded protein localizes to the nuclear matrix, PML nuclear bodies, and cytoplasmic vesicles. A highly similar gene in the mouse is required for localization of specific membrane proteins in polarized regions of neurons. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Gene Name: Spectrin Beta, Non-erythrocytic 4

Chromosome: CHR19: 40973125 -41082365

Locus: 19q13.2

Gene Diseases

The SAMD4B SPTBN4 Fusion has been associated with the following diseases:

Disease Name
Colon Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.