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SASH1-ARID1B Fusion FISH Probe

The SASH1-ARID1B Fusion FISH Probe is used to confirm a fusion of the SASH1 and ARID1B genes. The fusion of the SASH1 and ARID1B genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
SASH1-ARID1B-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
SASH1-ARID1B-20-RERE 20 (40 μL) 200 μL
SASH1-ARID1B-20-REOR 20 (40 μL) 200 μL
SASH1-ARID1B-20-REGO 20 (40 μL) 200 μL
SASH1-ARID1B-20-REGR 20 (40 μL) 200 μL
SASH1-ARID1B-20-REAQ 20 (40 μL) 200 μL
SASH1-ARID1B-20-ORRE 20 (40 μL) 200 μL
SASH1-ARID1B-20-OROR 20 (40 μL) 200 μL
SASH1-ARID1B-20-ORGO 20 (40 μL) 200 μL
SASH1-ARID1B-20-ORAQ 20 (40 μL) 200 μL
SASH1-ARID1B-20-GORE 20 (40 μL) 200 μL
SASH1-ARID1B-20-GOOR 20 (40 μL) 200 μL
SASH1-ARID1B-20-GOGO 20 (40 μL) 200 μL
SASH1-ARID1B-20-GOGR 20 (40 μL) 200 μL
SASH1-ARID1B-20-GOAQ 20 (40 μL) 200 μL
SASH1-ARID1B-20-GRRE 20 (40 μL) 200 μL
SASH1-ARID1B-20-GROR 20 (40 μL) 200 μL
SASH1-ARID1B-20-GRGO 20 (40 μL) 200 μL
SASH1-ARID1B-20-GRGR 20 (40 μL) 200 μL
SASH1-ARID1B-20-GRAQ 20 (40 μL) 200 μL
SASH1-ARID1B-20-AQRE 20 (40 μL) 200 μL
SASH1-ARID1B-20-AQOR 20 (40 μL) 200 μL
SASH1-ARID1B-20-AQGO 20 (40 μL) 200 μL
SASH1-ARID1B-20-AQGR 20 (40 μL) 200 μL
SASH1-ARID1B-20-AQAQ 20 (40 μL) 200 μL

SASH1 Gene Summary

This gene encodes a scaffold protein involved in the TLR4 signaling pathway that may stimulate cytokine production and endothelial cell migration in response to invading pathogens. The encoded protein has also been described as a potential tumor suppressor that may negatively regulate proliferation, apoptosis, and invasion of cancer cells, and reduced expression of this gene has been observed in multiple human cancers. Mutations in this gene may be associated with abnormal skin pigmentation in human patients. [provided by RefSeq, Oct 2016]

Gene Name: SAM And SH3 Domain Containing 1

Chromosome: CHR6: 148663728 -148873184

Locus: 6q24.3-q25.1

ARID1B Gene Summary

This locus encodes an AT-rich DNA interacting domain-containing protein. The encoded protein is a component of the SWI/SNF chromatin remodeling complex and may play a role in cell-cycle activation. The protein encoded by this locus is similar to AT-rich interactive domain-containing protein 1A. These two proteins function as alternative, mutually exclusive ARID-subunits of the SWI/SNF complex. The associated complexes play opposing roles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]

Gene Name: AT-rich Interaction Domain 1B

Chromosome: CHR6: 157099063 -157531913

Locus: 6q25.3

Gene Diseases

The SASH1 ARID1B Fusion has been associated with the following diseases:

Disease Name
Breast Invasive Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.