SBF2-FEZ1 Fusion FISH Probe
The SBF2-FEZ1 Fusion FISH Probe is used to confirm a fusion of the SBF2 and FEZ1 genes. The fusion of the SBF2 and FEZ1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SBF2-FEZ1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SBF2-FEZ1-20-RERE | 20 (40 μL) | 200 μL |
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| SBF2-FEZ1-20-REOR | 20 (40 μL) | 200 μL |
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| SBF2-FEZ1-20-REGO | 20 (40 μL) | 200 μL |
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| SBF2-FEZ1-20-REGR | 20 (40 μL) | 200 μL |
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| SBF2-FEZ1-20-REAQ | 20 (40 μL) | 200 μL |
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| SBF2-FEZ1-20-ORRE | 20 (40 μL) | 200 μL |
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| SBF2-FEZ1-20-OROR | 20 (40 μL) | 200 μL |
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| SBF2-FEZ1-20-ORGO | 20 (40 μL) | 200 μL |
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| SBF2-FEZ1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SBF2-FEZ1-20-GORE | 20 (40 μL) | 200 μL |
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| SBF2-FEZ1-20-GOOR | 20 (40 μL) | 200 μL |
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| SBF2-FEZ1-20-GOGO | 20 (40 μL) | 200 μL |
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| SBF2-FEZ1-20-GOGR | 20 (40 μL) | 200 μL |
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| SBF2-FEZ1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SBF2-FEZ1-20-GRRE | 20 (40 μL) | 200 μL |
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| SBF2-FEZ1-20-GROR | 20 (40 μL) | 200 μL |
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| SBF2-FEZ1-20-GRGO | 20 (40 μL) | 200 μL |
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| SBF2-FEZ1-20-GRGR | 20 (40 μL) | 200 μL |
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| SBF2-FEZ1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SBF2-FEZ1-20-AQRE | 20 (40 μL) | 200 μL |
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| SBF2-FEZ1-20-AQOR | 20 (40 μL) | 200 μL |
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| SBF2-FEZ1-20-AQGO | 20 (40 μL) | 200 μL |
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| SBF2-FEZ1-20-AQGR | 20 (40 μL) | 200 μL |
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| SBF2-FEZ1-20-AQAQ | 20 (40 μL) | 200 μL |
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FEZ1 Gene Summary
This gene is an ortholog of the C. elegans unc-76 gene, which is necessary for normal axonal bundling and elongation within axon bundles. Expression of this gene in C. elegans unc-76 mutants can restore to the mutants partial locomotion and axonal fasciculation, suggesting that it also functions in axonal outgrowth. The N-terminal half of the gene product is highly acidic. Alternatively spliced transcript variants encoding different isoforms of this protein have been described. [provided by RefSeq, Jul 2008]
Gene Name: Fasciculation And Elongation Protein Zeta 1
Chromosome: CHR11: 125315640 -125366206
Locus: 11q24.2
SBF2 Gene Summary
This gene encodes a pseudophosphatase and member of the myotubularin-related protein family. This gene maps within the CMT4B2 candidate region of chromosome 11p15 and mutations in this gene have been associated with Charcot-Marie-Tooth Disease, type 4B2. [provided by RefSeq, Jul 2008]
Gene Name: SET Binding Factor 2
Chromosome: CHR11: 9800213 -10315754
Locus: 11p15.4
Gene Diseases
The SBF2 FEZ1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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