SCAMP4-DAZAP1 Fusion FISH Probe
The SCAMP4-DAZAP1 Fusion FISH Probe is used to confirm a fusion of the SCAMP4 and DAZAP1 genes. The fusion of the SCAMP4 and DAZAP1 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SCAMP4-DAZAP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SCAMP4-DAZAP1-20-RERE | 20 (40 μL) | 200 μL |
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| SCAMP4-DAZAP1-20-REOR | 20 (40 μL) | 200 μL |
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| SCAMP4-DAZAP1-20-REGO | 20 (40 μL) | 200 μL |
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| SCAMP4-DAZAP1-20-REGR | 20 (40 μL) | 200 μL |
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| SCAMP4-DAZAP1-20-REAQ | 20 (40 μL) | 200 μL |
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| SCAMP4-DAZAP1-20-ORRE | 20 (40 μL) | 200 μL |
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| SCAMP4-DAZAP1-20-OROR | 20 (40 μL) | 200 μL |
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| SCAMP4-DAZAP1-20-ORGO | 20 (40 μL) | 200 μL |
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| SCAMP4-DAZAP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SCAMP4-DAZAP1-20-GORE | 20 (40 μL) | 200 μL |
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| SCAMP4-DAZAP1-20-GOOR | 20 (40 μL) | 200 μL |
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| SCAMP4-DAZAP1-20-GOGO | 20 (40 μL) | 200 μL |
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| SCAMP4-DAZAP1-20-GOGR | 20 (40 μL) | 200 μL |
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| SCAMP4-DAZAP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SCAMP4-DAZAP1-20-GRRE | 20 (40 μL) | 200 μL |
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| SCAMP4-DAZAP1-20-GROR | 20 (40 μL) | 200 μL |
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| SCAMP4-DAZAP1-20-GRGO | 20 (40 μL) | 200 μL |
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| SCAMP4-DAZAP1-20-GRGR | 20 (40 μL) | 200 μL |
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| SCAMP4-DAZAP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SCAMP4-DAZAP1-20-AQRE | 20 (40 μL) | 200 μL |
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| SCAMP4-DAZAP1-20-AQOR | 20 (40 μL) | 200 μL |
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| SCAMP4-DAZAP1-20-AQGO | 20 (40 μL) | 200 μL |
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| SCAMP4-DAZAP1-20-AQGR | 20 (40 μL) | 200 μL |
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| SCAMP4-DAZAP1-20-AQAQ | 20 (40 μL) | 200 μL |
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DAZAP1 Gene Summary
In mammals, the Y chromosome directs the development of the testes and plays an important role in spermatogenesis. A high percentage of infertile men have deletions that map to regions of the Y chromosome. The DAZ (deleted in azoospermia) gene cluster maps to the AZFc region of the Y chromosome and is deleted in many azoospermic and severely oligospermic men. It is thought that the DAZ gene cluster arose from the transposition, amplification, and pruning of the ancestral autosomal gene DAZL also involved in germ cell development and gametogenesis. This gene encodes a RNA-binding protein with two RNP motifs that was originally identified by its interaction with the infertility factors DAZ and DAZL. Two isoforms are encoded by transcript variants of this gene. [provided by RefSeq, Jul 2008]
Gene Name: DAZ Associated Protein 1
Chromosome: CHR19: 1407583 -1435682
Locus: 19p13.3
SCAMP4 Gene Summary
Secretory carrier membrane proteins (SCAMPs) are widely distributed integral membrane proteins implicated in membrane trafficking. Most SCAMPs (e.g., SCAMP1; MIM 606911) have N-terminal cytoplasmic NPF (arg-pro-phe) repeats, 4 central transmembrane regions, and a short C-terminal cytoplasmic tail. These SCAMPs likely have a role in endocytosis that is mediated by their NPF repeats. Other SCAMPs, such as SCAMP4, lack the NPF repeats and are therefore unlikely to function in endocytosis (summary by Fernandez-Chacon and Sudhof, 2000 [PubMed 11050114]).[supplied by OMIM, Feb 2011]
Gene Name: Secretory Carrier Membrane Protein 4
Chromosome: CHR19: 1905372 -1926012
Locus: 19p13.3
Gene Diseases
The SCAMP4 DAZAP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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