SCAP-SMARCC1 Fusion FISH Probe
The SCAP-SMARCC1 Fusion FISH Probe is used to confirm a fusion of the SCAP and SMARCC1 genes. The fusion of the SCAP and SMARCC1 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SCAP-SMARCC1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SCAP-SMARCC1-20-RERE | 20 (40 μL) | 200 μL |
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| SCAP-SMARCC1-20-REOR | 20 (40 μL) | 200 μL |
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| SCAP-SMARCC1-20-REGO | 20 (40 μL) | 200 μL |
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| SCAP-SMARCC1-20-REGR | 20 (40 μL) | 200 μL |
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| SCAP-SMARCC1-20-REAQ | 20 (40 μL) | 200 μL |
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| SCAP-SMARCC1-20-ORRE | 20 (40 μL) | 200 μL |
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| SCAP-SMARCC1-20-OROR | 20 (40 μL) | 200 μL |
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| SCAP-SMARCC1-20-ORGO | 20 (40 μL) | 200 μL |
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| SCAP-SMARCC1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SCAP-SMARCC1-20-GORE | 20 (40 μL) | 200 μL |
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| SCAP-SMARCC1-20-GOOR | 20 (40 μL) | 200 μL |
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| SCAP-SMARCC1-20-GOGO | 20 (40 μL) | 200 μL |
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| SCAP-SMARCC1-20-GOGR | 20 (40 μL) | 200 μL |
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| SCAP-SMARCC1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SCAP-SMARCC1-20-GRRE | 20 (40 μL) | 200 μL |
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| SCAP-SMARCC1-20-GROR | 20 (40 μL) | 200 μL |
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| SCAP-SMARCC1-20-GRGO | 20 (40 μL) | 200 μL |
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| SCAP-SMARCC1-20-GRGR | 20 (40 μL) | 200 μL |
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| SCAP-SMARCC1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SCAP-SMARCC1-20-AQRE | 20 (40 μL) | 200 μL |
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| SCAP-SMARCC1-20-AQOR | 20 (40 μL) | 200 μL |
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| SCAP-SMARCC1-20-AQGO | 20 (40 μL) | 200 μL |
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| SCAP-SMARCC1-20-AQGR | 20 (40 μL) | 200 μL |
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| SCAP-SMARCC1-20-AQAQ | 20 (40 μL) | 200 μL |
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SMARCC1 Gene Summary
The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors. [provided by RefSeq, Jul 2008]
Gene Name: SWI/SNF Related, Matrix Associated, Actin Dependent Regulator Of Chromatin Subfamily C Member 1
Chromosome: CHR3: 47627377 -47823405
Locus: 3p21.31
SCAP Gene Summary
This gene encodes a protein with a sterol sensing domain (SSD) and seven WD domains. In the presence of cholesterol, this protein binds to sterol regulatory element binding proteins (SREBPs) and mediates their transport from the ER to the Golgi. The SREBPs are then proteolytically cleaved and regulate sterol biosynthesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Gene Name: SREBF Chaperone
Chromosome: CHR3: 47455183 -47517445
Locus: 3p21.31
Gene Diseases
The SCAP SMARCC1 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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