SCD-SEC61A2 Fusion FISH Probe
The SCD-SEC61A2 Fusion FISH Probe is used to confirm a fusion of the SCD and SEC61A2 genes. The fusion of the SCD and SEC61A2 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SCD-SEC61A2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SCD-SEC61A2-20-RERE | 20 (40 μL) | 200 μL |
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| SCD-SEC61A2-20-REOR | 20 (40 μL) | 200 μL |
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| SCD-SEC61A2-20-REGO | 20 (40 μL) | 200 μL |
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| SCD-SEC61A2-20-REGR | 20 (40 μL) | 200 μL |
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| SCD-SEC61A2-20-REAQ | 20 (40 μL) | 200 μL |
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| SCD-SEC61A2-20-ORRE | 20 (40 μL) | 200 μL |
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| SCD-SEC61A2-20-OROR | 20 (40 μL) | 200 μL |
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| SCD-SEC61A2-20-ORGO | 20 (40 μL) | 200 μL |
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| SCD-SEC61A2-20-ORAQ | 20 (40 μL) | 200 μL |
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| SCD-SEC61A2-20-GORE | 20 (40 μL) | 200 μL |
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| SCD-SEC61A2-20-GOOR | 20 (40 μL) | 200 μL |
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| SCD-SEC61A2-20-GOGO | 20 (40 μL) | 200 μL |
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| SCD-SEC61A2-20-GOGR | 20 (40 μL) | 200 μL |
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| SCD-SEC61A2-20-GOAQ | 20 (40 μL) | 200 μL |
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| SCD-SEC61A2-20-GRRE | 20 (40 μL) | 200 μL |
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| SCD-SEC61A2-20-GROR | 20 (40 μL) | 200 μL |
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| SCD-SEC61A2-20-GRGO | 20 (40 μL) | 200 μL |
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| SCD-SEC61A2-20-GRGR | 20 (40 μL) | 200 μL |
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| SCD-SEC61A2-20-GRAQ | 20 (40 μL) | 200 μL |
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| SCD-SEC61A2-20-AQRE | 20 (40 μL) | 200 μL |
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| SCD-SEC61A2-20-AQOR | 20 (40 μL) | 200 μL |
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| SCD-SEC61A2-20-AQGO | 20 (40 μL) | 200 μL |
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| SCD-SEC61A2-20-AQGR | 20 (40 μL) | 200 μL |
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| SCD-SEC61A2-20-AQAQ | 20 (40 μL) | 200 μL |
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SCD Gene Summary
This gene encodes an enzyme involved in fatty acid biosynthesis, primarily the synthesis of oleic acid. The protein belongs to the fatty acid desaturase family and is an integral membrane protein located in the endoplasmic reticulum. Transcripts of approximately 3.9 and 5.2 kb, differing only by alternative polyadenlyation signals, have been detected. A gene encoding a similar enzyme is located on chromosome 4 and a pseudogene of this gene is located on chromosome 17. [provided by RefSeq, Sep 2015]
Gene Name: Stearoyl-CoA Desaturase
Chromosome: CHR10: 102106771 -102124588
Locus: 10q24.31
SEC61A2 Gene Summary
The protein encoded by this gene has similarity to a mouse protein which suggests a role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum. It may also be required for the assembly of membrane and secretory proteins. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]
Gene Name: Sec61 Translocon Alpha 2 Subunit
Chromosome: CHR10: 12171639 -12211957
Locus: 10p14
Gene Diseases
The SCD SEC61A2 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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