SEC61A1-ELK3 Fusion FISH Probe
The SEC61A1-ELK3 Fusion FISH Probe is used to confirm a fusion of the SEC61A1 and ELK3 genes. The fusion of the SEC61A1 and ELK3 genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SEC61A1-ELK3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SEC61A1-ELK3-20-RERE | 20 (40 μL) | 200 μL |
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| SEC61A1-ELK3-20-REOR | 20 (40 μL) | 200 μL |
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| SEC61A1-ELK3-20-REGO | 20 (40 μL) | 200 μL |
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| SEC61A1-ELK3-20-REGR | 20 (40 μL) | 200 μL |
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| SEC61A1-ELK3-20-REAQ | 20 (40 μL) | 200 μL |
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| SEC61A1-ELK3-20-ORRE | 20 (40 μL) | 200 μL |
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| SEC61A1-ELK3-20-OROR | 20 (40 μL) | 200 μL |
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| SEC61A1-ELK3-20-ORGO | 20 (40 μL) | 200 μL |
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| SEC61A1-ELK3-20-ORAQ | 20 (40 μL) | 200 μL |
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| SEC61A1-ELK3-20-GORE | 20 (40 μL) | 200 μL |
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| SEC61A1-ELK3-20-GOOR | 20 (40 μL) | 200 μL |
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| SEC61A1-ELK3-20-GOGO | 20 (40 μL) | 200 μL |
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| SEC61A1-ELK3-20-GOGR | 20 (40 μL) | 200 μL |
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| SEC61A1-ELK3-20-GOAQ | 20 (40 μL) | 200 μL |
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| SEC61A1-ELK3-20-GRRE | 20 (40 μL) | 200 μL |
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| SEC61A1-ELK3-20-GROR | 20 (40 μL) | 200 μL |
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| SEC61A1-ELK3-20-GRGO | 20 (40 μL) | 200 μL |
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| SEC61A1-ELK3-20-GRGR | 20 (40 μL) | 200 μL |
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| SEC61A1-ELK3-20-GRAQ | 20 (40 μL) | 200 μL |
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| SEC61A1-ELK3-20-AQRE | 20 (40 μL) | 200 μL |
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| SEC61A1-ELK3-20-AQOR | 20 (40 μL) | 200 μL |
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| SEC61A1-ELK3-20-AQGO | 20 (40 μL) | 200 μL |
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| SEC61A1-ELK3-20-AQGR | 20 (40 μL) | 200 μL |
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| SEC61A1-ELK3-20-AQAQ | 20 (40 μL) | 200 μL |
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ELK3 Gene Summary
This gene encodes a member of the ETS-domain transcription factor family and the ternary complex factor (TCF) subfamily. Proteins in this subfamily regulate transcription when recruited by serum response factor to bind to serum response elements. This protein is activated by signal-induced phosphorylation; studies in rodents suggest that it is a transcriptional inhibitor in the absence of Ras, but activates transcription when Ras is present. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]
Gene Name: ELK3, ETS Transcription Factor
Chromosome: CHR12: 96588206 -96661606
Locus: 12q23.1
SEC61A1 Gene Summary
The protein encoded by this gene belongs to the SECY/SEC61- alpha family. It appears to play a crucial role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum. This protein found to be tightly associated with membrane-bound ribosomes, either directly or through adaptor proteins. This gene encodes an alpha subunit of the heteromeric SEC61 complex, which also contains beta and gamma subunits. [provided by RefSeq, Jul 2008]
Gene Name: Sec61 Translocon Alpha 1 Subunit
Chromosome: CHR3: 127771211 -127790526
Locus: 3q21.3
Gene Diseases
The SEC61A1 ELK3 Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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