SEMA3C-CD36 Fusion FISH Probe
The SEMA3C-CD36 Fusion FISH Probe is used to confirm a fusion of the SEMA3C and CD36 genes. The fusion of the SEMA3C and CD36 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SEMA3C-CD36-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SEMA3C-CD36-20-RERE | 20 (40 μL) | 200 μL |
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| SEMA3C-CD36-20-REOR | 20 (40 μL) | 200 μL |
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| SEMA3C-CD36-20-REGO | 20 (40 μL) | 200 μL |
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| SEMA3C-CD36-20-REGR | 20 (40 μL) | 200 μL |
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| SEMA3C-CD36-20-REAQ | 20 (40 μL) | 200 μL |
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| SEMA3C-CD36-20-ORRE | 20 (40 μL) | 200 μL |
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| SEMA3C-CD36-20-OROR | 20 (40 μL) | 200 μL |
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| SEMA3C-CD36-20-ORGO | 20 (40 μL) | 200 μL |
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| SEMA3C-CD36-20-ORAQ | 20 (40 μL) | 200 μL |
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| SEMA3C-CD36-20-GORE | 20 (40 μL) | 200 μL |
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| SEMA3C-CD36-20-GOOR | 20 (40 μL) | 200 μL |
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| SEMA3C-CD36-20-GOGO | 20 (40 μL) | 200 μL |
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| SEMA3C-CD36-20-GOGR | 20 (40 μL) | 200 μL |
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| SEMA3C-CD36-20-GOAQ | 20 (40 μL) | 200 μL |
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| SEMA3C-CD36-20-GRRE | 20 (40 μL) | 200 μL |
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| SEMA3C-CD36-20-GROR | 20 (40 μL) | 200 μL |
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| SEMA3C-CD36-20-GRGO | 20 (40 μL) | 200 μL |
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| SEMA3C-CD36-20-GRGR | 20 (40 μL) | 200 μL |
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| SEMA3C-CD36-20-GRAQ | 20 (40 μL) | 200 μL |
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| SEMA3C-CD36-20-AQRE | 20 (40 μL) | 200 μL |
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| SEMA3C-CD36-20-AQOR | 20 (40 μL) | 200 μL |
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| SEMA3C-CD36-20-AQGO | 20 (40 μL) | 200 μL |
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| SEMA3C-CD36-20-AQGR | 20 (40 μL) | 200 μL |
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| SEMA3C-CD36-20-AQAQ | 20 (40 μL) | 200 μL |
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CD36 Gene Summary
The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2014]
Gene Name: CD36 Molecule
Chromosome: CHR7: 80231503 -80303734
Locus: 7q21.11
SEMA3C Gene Summary
This gene encodes a secreted glycoprotein that belongs to the semaphorin class 3 family of neuronal guidance cues. The encoded protein contains an N-terminal sema domain, integrin and immunoglobulin-like domains, and a C-terminal basic domain. Homodimerization and proteolytic cleavage of the C-terminal propeptide are necessary for the function of the encoded protein. It binds a neuropilin co-receptor before forming a heterotrimeric complex with an associated plexin. An increase in the expression of this gene correlates with an increase in cancer cell invasion and adhesion. Naturally occurring mutations in this gene are associated with Hirschsprung disease. [provided by RefSeq, May 2017]
Gene Name: Semaphorin 3C
Chromosome: CHR7: 80371853 -80548667
Locus: 7q21.11
Gene Diseases
The SEMA3C CD36 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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