SEMA3D-RBM28 Fusion FISH Probe
The SEMA3D-RBM28 Fusion FISH Probe is used to confirm a fusion of the SEMA3D and RBM28 genes. The fusion of the SEMA3D and RBM28 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SEMA3D-RBM28-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SEMA3D-RBM28-20-RERE | 20 (40 μL) | 200 μL |
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| SEMA3D-RBM28-20-REOR | 20 (40 μL) | 200 μL |
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| SEMA3D-RBM28-20-REGO | 20 (40 μL) | 200 μL |
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| SEMA3D-RBM28-20-REGR | 20 (40 μL) | 200 μL |
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| SEMA3D-RBM28-20-REAQ | 20 (40 μL) | 200 μL |
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| SEMA3D-RBM28-20-ORRE | 20 (40 μL) | 200 μL |
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| SEMA3D-RBM28-20-OROR | 20 (40 μL) | 200 μL |
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| SEMA3D-RBM28-20-ORGO | 20 (40 μL) | 200 μL |
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| SEMA3D-RBM28-20-ORAQ | 20 (40 μL) | 200 μL |
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| SEMA3D-RBM28-20-GORE | 20 (40 μL) | 200 μL |
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| SEMA3D-RBM28-20-GOOR | 20 (40 μL) | 200 μL |
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| SEMA3D-RBM28-20-GOGO | 20 (40 μL) | 200 μL |
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| SEMA3D-RBM28-20-GOGR | 20 (40 μL) | 200 μL |
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| SEMA3D-RBM28-20-GOAQ | 20 (40 μL) | 200 μL |
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| SEMA3D-RBM28-20-GRRE | 20 (40 μL) | 200 μL |
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| SEMA3D-RBM28-20-GROR | 20 (40 μL) | 200 μL |
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| SEMA3D-RBM28-20-GRGO | 20 (40 μL) | 200 μL |
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| SEMA3D-RBM28-20-GRGR | 20 (40 μL) | 200 μL |
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| SEMA3D-RBM28-20-GRAQ | 20 (40 μL) | 200 μL |
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| SEMA3D-RBM28-20-AQRE | 20 (40 μL) | 200 μL |
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| SEMA3D-RBM28-20-AQOR | 20 (40 μL) | 200 μL |
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| SEMA3D-RBM28-20-AQGO | 20 (40 μL) | 200 μL |
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| SEMA3D-RBM28-20-AQGR | 20 (40 μL) | 200 μL |
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| SEMA3D-RBM28-20-AQAQ | 20 (40 μL) | 200 μL |
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RBM28 Gene Summary
The protein encoded by this gene is a specific nucleolar component of the spliceosomal small nuclear ribonucleoprotein (snRNP)complexes . It specifically associates with U1, U2, U4, U5, and U6 small nuclear RNAs (snRNAs), possibly coordinating their transition through the nucleolus. Mutation in this gene causes alopecia, progressive neurological defects, and endocrinopathy (ANE syndrome), a pleiotropic and clinically heterogeneous disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]
Gene Name: RNA Binding Motif Protein 28
Chromosome: CHR7: 127950435 -127983962
Locus: 7q32.1
SEMA3D Gene Summary
This gene encodes a member of the semaphorin III family of secreted signaling proteins that are involved in axon guidance during neuronal development. The encoded protein contains an N-terminal Sema domain, an immunoglobulin like domain and a C-terminal basic domain. The protein encoded by this gene binds neuropilin and plays an important role in cardiovascular development. [provided by RefSeq, Aug 2016]
Gene Name: Semaphorin 3D
Chromosome: CHR7: 84624871 -84751247
Locus: 7q21.11
Gene Diseases
The SEMA3D RBM28 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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