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SENP2-MSH5 Fusion FISH Probe

The SENP2-MSH5 Fusion FISH Probe is used to confirm a fusion of the SENP2 and MSH5 genes. The fusion of the SENP2 and MSH5 genes has been associated with Adrenocortical Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
SENP2-MSH5-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
SENP2-MSH5-20-RERE 20 (40 μL) 200 μL
SENP2-MSH5-20-REOR 20 (40 μL) 200 μL
SENP2-MSH5-20-REGO 20 (40 μL) 200 μL
SENP2-MSH5-20-REGR 20 (40 μL) 200 μL
SENP2-MSH5-20-REAQ 20 (40 μL) 200 μL
SENP2-MSH5-20-ORRE 20 (40 μL) 200 μL
SENP2-MSH5-20-OROR 20 (40 μL) 200 μL
SENP2-MSH5-20-ORGO 20 (40 μL) 200 μL
SENP2-MSH5-20-ORAQ 20 (40 μL) 200 μL
SENP2-MSH5-20-GORE 20 (40 μL) 200 μL
SENP2-MSH5-20-GOOR 20 (40 μL) 200 μL
SENP2-MSH5-20-GOGO 20 (40 μL) 200 μL
SENP2-MSH5-20-GOGR 20 (40 μL) 200 μL
SENP2-MSH5-20-GOAQ 20 (40 μL) 200 μL
SENP2-MSH5-20-GRRE 20 (40 μL) 200 μL
SENP2-MSH5-20-GROR 20 (40 μL) 200 μL
SENP2-MSH5-20-GRGO 20 (40 μL) 200 μL
SENP2-MSH5-20-GRGR 20 (40 μL) 200 μL
SENP2-MSH5-20-GRAQ 20 (40 μL) 200 μL
SENP2-MSH5-20-AQRE 20 (40 μL) 200 μL
SENP2-MSH5-20-AQOR 20 (40 μL) 200 μL
SENP2-MSH5-20-AQGO 20 (40 μL) 200 μL
SENP2-MSH5-20-AQGR 20 (40 μL) 200 μL
SENP2-MSH5-20-AQAQ 20 (40 μL) 200 μL

MSH5 Gene Summary

This gene encodes a member of the mutS family of proteins that are involved in DNA mismatch repair and meiotic recombination. This protein is similar to a Saccharomyces cerevisiae protein that participates in segregation fidelity and crossing-over events during meiosis. This protein plays a role in promoting ionizing radiation-induced apoptosis. This protein forms hetero-oligomers with another member of this family, mutS homolog 4. Polymorphisms in this gene have been linked to various human diseases, including IgA deficiency, common variable immunodeficiency, and premature ovarian failure. Alternative splicing results multiple transcript variants. Read-through transcription also exists between this gene and the downstream chromosome 6 open reading frame 26 (C6orf26) gene. [provided by RefSeq, Feb 2011]

Gene Name: MutS Homolog 5

Chromosome: CHR6_mcf_hap5: 3087408 -3110152

Locus: 6p21.33

SENP2 Gene Summary

SUMO1 (UBL1; MIM 601912) is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1 into the conjugatable form and catalyze the deconjugation of SUMO1-containing species.[supplied by OMIM, Apr 2004]

Gene Name: SUMO1/sentrin/SMT3 Specific Peptidase 2

Chromosome: CHR3: 185304030 -185348885

Locus: 3q27.2

Gene Diseases

The SENP2 MSH5 Fusion has been associated with the following diseases:

Disease Name
Adrenocortical Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.