SERGEF-HBE1 Fusion FISH Probe
The SERGEF-HBE1 Fusion FISH Probe is used to confirm a fusion of the SERGEF and HBE1 genes. The fusion of the SERGEF and HBE1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SERGEF-HBE1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SERGEF-HBE1-20-RERE | 20 (40 μL) | 200 μL |
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| SERGEF-HBE1-20-REOR | 20 (40 μL) | 200 μL |
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| SERGEF-HBE1-20-REGO | 20 (40 μL) | 200 μL |
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| SERGEF-HBE1-20-REGR | 20 (40 μL) | 200 μL |
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| SERGEF-HBE1-20-REAQ | 20 (40 μL) | 200 μL |
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| SERGEF-HBE1-20-ORRE | 20 (40 μL) | 200 μL |
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| SERGEF-HBE1-20-OROR | 20 (40 μL) | 200 μL |
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| SERGEF-HBE1-20-ORGO | 20 (40 μL) | 200 μL |
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| SERGEF-HBE1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SERGEF-HBE1-20-GORE | 20 (40 μL) | 200 μL |
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| SERGEF-HBE1-20-GOOR | 20 (40 μL) | 200 μL |
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| SERGEF-HBE1-20-GOGO | 20 (40 μL) | 200 μL |
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| SERGEF-HBE1-20-GOGR | 20 (40 μL) | 200 μL |
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| SERGEF-HBE1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SERGEF-HBE1-20-GRRE | 20 (40 μL) | 200 μL |
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| SERGEF-HBE1-20-GROR | 20 (40 μL) | 200 μL |
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| SERGEF-HBE1-20-GRGO | 20 (40 μL) | 200 μL |
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| SERGEF-HBE1-20-GRGR | 20 (40 μL) | 200 μL |
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| SERGEF-HBE1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SERGEF-HBE1-20-AQRE | 20 (40 μL) | 200 μL |
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| SERGEF-HBE1-20-AQOR | 20 (40 μL) | 200 μL |
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| SERGEF-HBE1-20-AQGO | 20 (40 μL) | 200 μL |
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| SERGEF-HBE1-20-AQGR | 20 (40 μL) | 200 μL |
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| SERGEF-HBE1-20-AQAQ | 20 (40 μL) | 200 μL |
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HBE1 Gene Summary
The epsilon globin gene (HBE) is normally expressed in the embryonic yolk sac: two epsilon chains together with two zeta chains (an alpha-like globin) constitute the embryonic hemoglobin Hb Gower I; two epsilon chains together with two alpha chains form the embryonic Hb Gower II. Both of these embryonic hemoglobins are normally supplanted by fetal, and later, adult hemoglobin. The five beta-like globin genes are found within a 45 kb cluster on chromosome 11 in the following order: 5'-epsilon - G-gamma - A-gamma - delta - beta-3' [provided by RefSeq, Jul 2008]
Gene Name: Hemoglobin Subunit Epsilon 1
Chromosome: CHR11: 5289579 -5291373
Locus: 11p15.4
SERGEF Gene Summary
The Secretion Regulating Guanine Nucleotide Exchange Factor (SERGEF) gene is located on chr11 :17809596-18034637 at 11p15.1.
Gene Name: Secretion Regulating Guanine Nucleotide Exchange Factor
Chromosome: CHR11: 17809596 -18034637
Locus: 11p15.1
Gene Diseases
The SERGEF HBE1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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