SERGEF-KCNC1 Fusion FISH Probe
The SERGEF-KCNC1 Fusion FISH Probe is used to confirm a fusion of the SERGEF and KCNC1 genes. The fusion of the SERGEF and KCNC1 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SERGEF-KCNC1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SERGEF-KCNC1-20-RERE | 20 (40 μL) | 200 μL |
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| SERGEF-KCNC1-20-REOR | 20 (40 μL) | 200 μL |
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| SERGEF-KCNC1-20-REGO | 20 (40 μL) | 200 μL |
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| SERGEF-KCNC1-20-REGR | 20 (40 μL) | 200 μL |
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| SERGEF-KCNC1-20-REAQ | 20 (40 μL) | 200 μL |
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| SERGEF-KCNC1-20-ORRE | 20 (40 μL) | 200 μL |
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| SERGEF-KCNC1-20-OROR | 20 (40 μL) | 200 μL |
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| SERGEF-KCNC1-20-ORGO | 20 (40 μL) | 200 μL |
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| SERGEF-KCNC1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SERGEF-KCNC1-20-GORE | 20 (40 μL) | 200 μL |
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| SERGEF-KCNC1-20-GOOR | 20 (40 μL) | 200 μL |
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| SERGEF-KCNC1-20-GOGO | 20 (40 μL) | 200 μL |
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| SERGEF-KCNC1-20-GOGR | 20 (40 μL) | 200 μL |
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| SERGEF-KCNC1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SERGEF-KCNC1-20-GRRE | 20 (40 μL) | 200 μL |
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| SERGEF-KCNC1-20-GROR | 20 (40 μL) | 200 μL |
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| SERGEF-KCNC1-20-GRGO | 20 (40 μL) | 200 μL |
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| SERGEF-KCNC1-20-GRGR | 20 (40 μL) | 200 μL |
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| SERGEF-KCNC1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SERGEF-KCNC1-20-AQRE | 20 (40 μL) | 200 μL |
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| SERGEF-KCNC1-20-AQOR | 20 (40 μL) | 200 μL |
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| SERGEF-KCNC1-20-AQGO | 20 (40 μL) | 200 μL |
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| SERGEF-KCNC1-20-AQGR | 20 (40 μL) | 200 μL |
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| SERGEF-KCNC1-20-AQAQ | 20 (40 μL) | 200 μL |
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KCNC1 Gene Summary
This gene encodes a member of a family of integral membrane proteins that mediate the voltage-dependent potassium ion permeability of excitable membranes. Alternative splicing is thought to result in two transcript variants encoding isoforms that differ at their C-termini. These isoforms have had conflicting names in the literature: the longer isoform has been called both "b" and "alpha", while the shorter isoform has been called both "a" and "beta" (PMIDs 1432046, 12091563). [provided by RefSeq, Oct 2014]
Gene Name: Potassium Voltage-gated Channel Subfamily C Member 1
Chromosome: CHR11: 17757494 -17804602
Locus: 11p15.1
SERGEF Gene Summary
The Secretion Regulating Guanine Nucleotide Exchange Factor (SERGEF) gene is located on chr11 :17809596-18034637 at 11p15.1.
Gene Name: Secretion Regulating Guanine Nucleotide Exchange Factor
Chromosome: CHR11: 17809596 -18034637
Locus: 11p15.1
Gene Diseases
The SERGEF KCNC1 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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