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SERINC5-THBS4 Fusion FISH Probe

The SERINC5-THBS4 Fusion FISH Probe is used to confirm a fusion of the SERINC5 and THBS4 genes. The fusion of the SERINC5 and THBS4 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
SERINC5-THBS4-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
SERINC5-THBS4-20-RERE 20 (40 μL) 200 μL
SERINC5-THBS4-20-REOR 20 (40 μL) 200 μL
SERINC5-THBS4-20-REGO 20 (40 μL) 200 μL
SERINC5-THBS4-20-REGR 20 (40 μL) 200 μL
SERINC5-THBS4-20-REAQ 20 (40 μL) 200 μL
SERINC5-THBS4-20-ORRE 20 (40 μL) 200 μL
SERINC5-THBS4-20-OROR 20 (40 μL) 200 μL
SERINC5-THBS4-20-ORGO 20 (40 μL) 200 μL
SERINC5-THBS4-20-ORAQ 20 (40 μL) 200 μL
SERINC5-THBS4-20-GORE 20 (40 μL) 200 μL
SERINC5-THBS4-20-GOOR 20 (40 μL) 200 μL
SERINC5-THBS4-20-GOGO 20 (40 μL) 200 μL
SERINC5-THBS4-20-GOGR 20 (40 μL) 200 μL
SERINC5-THBS4-20-GOAQ 20 (40 μL) 200 μL
SERINC5-THBS4-20-GRRE 20 (40 μL) 200 μL
SERINC5-THBS4-20-GROR 20 (40 μL) 200 μL
SERINC5-THBS4-20-GRGO 20 (40 μL) 200 μL
SERINC5-THBS4-20-GRGR 20 (40 μL) 200 μL
SERINC5-THBS4-20-GRAQ 20 (40 μL) 200 μL
SERINC5-THBS4-20-AQRE 20 (40 μL) 200 μL
SERINC5-THBS4-20-AQOR 20 (40 μL) 200 μL
SERINC5-THBS4-20-AQGO 20 (40 μL) 200 μL
SERINC5-THBS4-20-AQGR 20 (40 μL) 200 μL
SERINC5-THBS4-20-AQAQ 20 (40 μL) 200 μL

THBS4 Gene Summary

The protein encoded by this gene belongs to the thrombospondin protein family. Thrombospondin family members are adhesive glycoproteins that mediate cell-to-cell and cell-to-matrix interactions. This protein forms a pentamer and can bind to heparin and calcium. It is involved in local signaling in the developing and adult nervous system, and it contributes to spinal sensitization and neuropathic pain states. This gene is activated during the stromal response to invasive breast cancer. It may also play a role in inflammatory responses in Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

Gene Name: Thrombospondin 4

Chromosome: CHR5: 79331169 -79379107

Locus: 5q14.1

SERINC5 Gene Summary

The Serine Incorporator 5 (SERINC5) gene is located on chr5 :79407049-79551898 at 5q14.1.

Gene Name: Serine Incorporator 5

Chromosome: CHR5: 79407049 -79551898

Locus: 5q14.1

Gene Diseases

The SERINC5 THBS4 Fusion has been associated with the following diseases:

Disease Name
Lung Squamous Cell Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.