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SESN1-ECHDC1 Fusion FISH Probe

The SESN1-ECHDC1 Fusion FISH Probe is used to confirm a fusion of the SESN1 and ECHDC1 genes. The fusion of the SESN1 and ECHDC1 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
SESN1-ECHDC1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
SESN1-ECHDC1-20-RERE 20 (40 μL) 200 μL
SESN1-ECHDC1-20-REOR 20 (40 μL) 200 μL
SESN1-ECHDC1-20-REGO 20 (40 μL) 200 μL
SESN1-ECHDC1-20-REGR 20 (40 μL) 200 μL
SESN1-ECHDC1-20-REAQ 20 (40 μL) 200 μL
SESN1-ECHDC1-20-ORRE 20 (40 μL) 200 μL
SESN1-ECHDC1-20-OROR 20 (40 μL) 200 μL
SESN1-ECHDC1-20-ORGO 20 (40 μL) 200 μL
SESN1-ECHDC1-20-ORAQ 20 (40 μL) 200 μL
SESN1-ECHDC1-20-GORE 20 (40 μL) 200 μL
SESN1-ECHDC1-20-GOOR 20 (40 μL) 200 μL
SESN1-ECHDC1-20-GOGO 20 (40 μL) 200 μL
SESN1-ECHDC1-20-GOGR 20 (40 μL) 200 μL
SESN1-ECHDC1-20-GOAQ 20 (40 μL) 200 μL
SESN1-ECHDC1-20-GRRE 20 (40 μL) 200 μL
SESN1-ECHDC1-20-GROR 20 (40 μL) 200 μL
SESN1-ECHDC1-20-GRGO 20 (40 μL) 200 μL
SESN1-ECHDC1-20-GRGR 20 (40 μL) 200 μL
SESN1-ECHDC1-20-GRAQ 20 (40 μL) 200 μL
SESN1-ECHDC1-20-AQRE 20 (40 μL) 200 μL
SESN1-ECHDC1-20-AQOR 20 (40 μL) 200 μL
SESN1-ECHDC1-20-AQGO 20 (40 μL) 200 μL
SESN1-ECHDC1-20-AQGR 20 (40 μL) 200 μL
SESN1-ECHDC1-20-AQAQ 20 (40 μL) 200 μL

SESN1 Gene Summary

This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]

Gene Name: Sestrin 1

Chromosome: CHR6: 109307639 -109415708

Locus: 6q21

ECHDC1 Gene Summary

The Ethylmalonyl-CoA Decarboxylase 1 (ECHDC1) gene is located on chr6 :127609856-127664754 at 6q22.33.

Gene Name: Ethylmalonyl-CoA Decarboxylase 1

Chromosome: CHR6: 127609856 -127664754

Locus: 6q22.33

Gene Diseases

The SESN1 ECHDC1 Fusion has been associated with the following diseases:

Disease Name
Lung Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.