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SETD2-CCRL2 Fusion FISH Probe

The SETD2-CCRL2 Fusion FISH Probe is used to confirm a fusion of the SETD2 and CCRL2 genes. The fusion of the SETD2 and CCRL2 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
SETD2-CCRL2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
SETD2-CCRL2-20-RERE 20 (40 μL) 200 μL
SETD2-CCRL2-20-REOR 20 (40 μL) 200 μL
SETD2-CCRL2-20-REGO 20 (40 μL) 200 μL
SETD2-CCRL2-20-REGR 20 (40 μL) 200 μL
SETD2-CCRL2-20-REAQ 20 (40 μL) 200 μL
SETD2-CCRL2-20-ORRE 20 (40 μL) 200 μL
SETD2-CCRL2-20-OROR 20 (40 μL) 200 μL
SETD2-CCRL2-20-ORGO 20 (40 μL) 200 μL
SETD2-CCRL2-20-ORAQ 20 (40 μL) 200 μL
SETD2-CCRL2-20-GORE 20 (40 μL) 200 μL
SETD2-CCRL2-20-GOOR 20 (40 μL) 200 μL
SETD2-CCRL2-20-GOGO 20 (40 μL) 200 μL
SETD2-CCRL2-20-GOGR 20 (40 μL) 200 μL
SETD2-CCRL2-20-GOAQ 20 (40 μL) 200 μL
SETD2-CCRL2-20-GRRE 20 (40 μL) 200 μL
SETD2-CCRL2-20-GROR 20 (40 μL) 200 μL
SETD2-CCRL2-20-GRGO 20 (40 μL) 200 μL
SETD2-CCRL2-20-GRGR 20 (40 μL) 200 μL
SETD2-CCRL2-20-GRAQ 20 (40 μL) 200 μL
SETD2-CCRL2-20-AQRE 20 (40 μL) 200 μL
SETD2-CCRL2-20-AQOR 20 (40 μL) 200 μL
SETD2-CCRL2-20-AQGO 20 (40 μL) 200 μL
SETD2-CCRL2-20-AQGR 20 (40 μL) 200 μL
SETD2-CCRL2-20-AQAQ 20 (40 μL) 200 μL

CCRL2 Gene Summary

This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located. [provided by RefSeq, Jul 2008]

Gene Name: C-C Motif Chemokine Receptor Like 2

Chromosome: CHR3: 46448720 -46451014

Locus: 3p21.31

SETD2 Gene Summary

Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]

Gene Name: SET Domain Containing 2

Chromosome: CHR3: 47057897 -47205467

Locus: 3p21.31

Gene Diseases

The SETD2 CCRL2 Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.