SETD2-MACROD2 Fusion FISH Probe
The SETD2-MACROD2 Fusion FISH Probe is used to confirm a fusion of the SETD2 and MACROD2 genes. The fusion of the SETD2 and MACROD2 genes has been associated with Mesothelioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SETD2-MACROD2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SETD2-MACROD2-20-RERE | 20 (40 μL) | 200 μL |
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| SETD2-MACROD2-20-REOR | 20 (40 μL) | 200 μL |
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| SETD2-MACROD2-20-REGO | 20 (40 μL) | 200 μL |
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| SETD2-MACROD2-20-REGR | 20 (40 μL) | 200 μL |
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| SETD2-MACROD2-20-REAQ | 20 (40 μL) | 200 μL |
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| SETD2-MACROD2-20-ORRE | 20 (40 μL) | 200 μL |
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| SETD2-MACROD2-20-OROR | 20 (40 μL) | 200 μL |
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| SETD2-MACROD2-20-ORGO | 20 (40 μL) | 200 μL |
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| SETD2-MACROD2-20-ORAQ | 20 (40 μL) | 200 μL |
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| SETD2-MACROD2-20-GORE | 20 (40 μL) | 200 μL |
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| SETD2-MACROD2-20-GOOR | 20 (40 μL) | 200 μL |
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| SETD2-MACROD2-20-GOGO | 20 (40 μL) | 200 μL |
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| SETD2-MACROD2-20-GOGR | 20 (40 μL) | 200 μL |
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| SETD2-MACROD2-20-GOAQ | 20 (40 μL) | 200 μL |
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| SETD2-MACROD2-20-GRRE | 20 (40 μL) | 200 μL |
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| SETD2-MACROD2-20-GROR | 20 (40 μL) | 200 μL |
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| SETD2-MACROD2-20-GRGO | 20 (40 μL) | 200 μL |
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| SETD2-MACROD2-20-GRGR | 20 (40 μL) | 200 μL |
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| SETD2-MACROD2-20-GRAQ | 20 (40 μL) | 200 μL |
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| SETD2-MACROD2-20-AQRE | 20 (40 μL) | 200 μL |
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| SETD2-MACROD2-20-AQOR | 20 (40 μL) | 200 μL |
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| SETD2-MACROD2-20-AQGO | 20 (40 μL) | 200 μL |
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| SETD2-MACROD2-20-AQGR | 20 (40 μL) | 200 μL |
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| SETD2-MACROD2-20-AQAQ | 20 (40 μL) | 200 μL |
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SETD2 Gene Summary
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]
Gene Name: SET Domain Containing 2
Chromosome: CHR3: 47057897 -47205467
Locus: 3p21.31
MACROD2 Gene Summary
The protein encoded by this gene is a deacetylase involved in removing ADP-ribose from mono-ADP-ribosylated proteins. The encoded protein has been shown to translocate from the nucleus to the cytoplasm upon DNA damage. [provided by RefSeq, May 2017]
Gene Name: MACRO Domain Containing 2
Chromosome: CHR20: 13976145 -16033841
Locus: 20p12.1
Gene Diseases
The SETD2 MACROD2 Fusion has been associated with the following diseases:
| Disease Name |
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| Mesothelioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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