SETDB1-PLEKHO1 Fusion FISH Probe
The SETDB1-PLEKHO1 Fusion FISH Probe is used to confirm a fusion of the SETDB1 and PLEKHO1 genes. The fusion of the SETDB1 and PLEKHO1 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SETDB1-PLEKHO1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SETDB1-PLEKHO1-20-RERE | 20 (40 μL) | 200 μL |
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| SETDB1-PLEKHO1-20-REOR | 20 (40 μL) | 200 μL |
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| SETDB1-PLEKHO1-20-REGO | 20 (40 μL) | 200 μL |
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| SETDB1-PLEKHO1-20-REGR | 20 (40 μL) | 200 μL |
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| SETDB1-PLEKHO1-20-REAQ | 20 (40 μL) | 200 μL |
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| SETDB1-PLEKHO1-20-ORRE | 20 (40 μL) | 200 μL |
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| SETDB1-PLEKHO1-20-OROR | 20 (40 μL) | 200 μL |
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| SETDB1-PLEKHO1-20-ORGO | 20 (40 μL) | 200 μL |
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| SETDB1-PLEKHO1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SETDB1-PLEKHO1-20-GORE | 20 (40 μL) | 200 μL |
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| SETDB1-PLEKHO1-20-GOOR | 20 (40 μL) | 200 μL |
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| SETDB1-PLEKHO1-20-GOGO | 20 (40 μL) | 200 μL |
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| SETDB1-PLEKHO1-20-GOGR | 20 (40 μL) | 200 μL |
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| SETDB1-PLEKHO1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SETDB1-PLEKHO1-20-GRRE | 20 (40 μL) | 200 μL |
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| SETDB1-PLEKHO1-20-GROR | 20 (40 μL) | 200 μL |
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| SETDB1-PLEKHO1-20-GRGO | 20 (40 μL) | 200 μL |
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| SETDB1-PLEKHO1-20-GRGR | 20 (40 μL) | 200 μL |
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| SETDB1-PLEKHO1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SETDB1-PLEKHO1-20-AQRE | 20 (40 μL) | 200 μL |
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| SETDB1-PLEKHO1-20-AQOR | 20 (40 μL) | 200 μL |
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| SETDB1-PLEKHO1-20-AQGO | 20 (40 μL) | 200 μL |
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| SETDB1-PLEKHO1-20-AQGR | 20 (40 μL) | 200 μL |
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| SETDB1-PLEKHO1-20-AQAQ | 20 (40 μL) | 200 μL |
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SETDB1 Gene Summary
This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.[provided by RefSeq, Jun 2011]
Gene Name: SET Domain Bifurcated 1
Chromosome: CHR1: 150898814 -150937220
Locus: 1q21.3
PLEKHO1 Gene Summary
The Pleckstrin Homology Domain Containing O1 (PLEKHO1) gene is located on chr1 :150122169-150131825 at 1q21.2.
Gene Name: Pleckstrin Homology Domain Containing O1
Chromosome: CHR1: 150122169 -150131825
Locus: 1q21.2
Gene Diseases
The SETDB1 PLEKHO1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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