SETMAR-EYS Fusion FISH Probe
The SETMAR-EYS Fusion FISH Probe is used to confirm a fusion of the SETMAR and EYS genes. The fusion of the SETMAR and EYS genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SETMAR-EYS-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SETMAR-EYS-20-RERE | 20 (40 μL) | 200 μL |
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| SETMAR-EYS-20-REOR | 20 (40 μL) | 200 μL |
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| SETMAR-EYS-20-REGO | 20 (40 μL) | 200 μL |
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| SETMAR-EYS-20-REGR | 20 (40 μL) | 200 μL |
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| SETMAR-EYS-20-REAQ | 20 (40 μL) | 200 μL |
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| SETMAR-EYS-20-ORRE | 20 (40 μL) | 200 μL |
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| SETMAR-EYS-20-OROR | 20 (40 μL) | 200 μL |
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| SETMAR-EYS-20-ORGO | 20 (40 μL) | 200 μL |
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| SETMAR-EYS-20-ORAQ | 20 (40 μL) | 200 μL |
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| SETMAR-EYS-20-GORE | 20 (40 μL) | 200 μL |
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| SETMAR-EYS-20-GOOR | 20 (40 μL) | 200 μL |
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| SETMAR-EYS-20-GOGO | 20 (40 μL) | 200 μL |
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| SETMAR-EYS-20-GOGR | 20 (40 μL) | 200 μL |
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| SETMAR-EYS-20-GOAQ | 20 (40 μL) | 200 μL |
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| SETMAR-EYS-20-GRRE | 20 (40 μL) | 200 μL |
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| SETMAR-EYS-20-GROR | 20 (40 μL) | 200 μL |
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| SETMAR-EYS-20-GRGO | 20 (40 μL) | 200 μL |
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| SETMAR-EYS-20-GRGR | 20 (40 μL) | 200 μL |
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| SETMAR-EYS-20-GRAQ | 20 (40 μL) | 200 μL |
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| SETMAR-EYS-20-AQRE | 20 (40 μL) | 200 μL |
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| SETMAR-EYS-20-AQOR | 20 (40 μL) | 200 μL |
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| SETMAR-EYS-20-AQGO | 20 (40 μL) | 200 μL |
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| SETMAR-EYS-20-AQGR | 20 (40 μL) | 200 μL |
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| SETMAR-EYS-20-AQAQ | 20 (40 μL) | 200 μL |
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SETMAR Gene Summary
This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
Gene Name: SET Domain And Mariner Transposase Fusion Gene
Chromosome: CHR3: 4344987 -4358949
Locus: 3p26.1
EYS Gene Summary
The product of this gene contains multiple epidermal growth factor (EGF)-like and LamG domains. The protein is expressed in the photoreceptor layer of the retina, and the gene is mutated in autosomal recessive retinitis pigmentosa. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Gene Name: Eyes Shut Homolog (Drosophila)
Chromosome: CHR6: 64429875 -66417118
Locus: 6q12
Gene Diseases
The SETMAR EYS Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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