SFN-TYK2 Fusion FISH Probe
The SFN-TYK2 Fusion FISH Probe is used to confirm a fusion of the SFN and TYK2 genes. The fusion of the SFN and TYK2 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SFN-TYK2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SFN-TYK2-20-RERE | 20 (40 μL) | 200 μL |
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| SFN-TYK2-20-REOR | 20 (40 μL) | 200 μL |
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| SFN-TYK2-20-REGO | 20 (40 μL) | 200 μL |
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| SFN-TYK2-20-REGR | 20 (40 μL) | 200 μL |
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| SFN-TYK2-20-REAQ | 20 (40 μL) | 200 μL |
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| SFN-TYK2-20-ORRE | 20 (40 μL) | 200 μL |
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| SFN-TYK2-20-OROR | 20 (40 μL) | 200 μL |
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| SFN-TYK2-20-ORGO | 20 (40 μL) | 200 μL |
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| SFN-TYK2-20-ORAQ | 20 (40 μL) | 200 μL |
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| SFN-TYK2-20-GORE | 20 (40 μL) | 200 μL |
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| SFN-TYK2-20-GOOR | 20 (40 μL) | 200 μL |
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| SFN-TYK2-20-GOGO | 20 (40 μL) | 200 μL |
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| SFN-TYK2-20-GOGR | 20 (40 μL) | 200 μL |
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| SFN-TYK2-20-GOAQ | 20 (40 μL) | 200 μL |
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| SFN-TYK2-20-GRRE | 20 (40 μL) | 200 μL |
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| SFN-TYK2-20-GROR | 20 (40 μL) | 200 μL |
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| SFN-TYK2-20-GRGO | 20 (40 μL) | 200 μL |
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| SFN-TYK2-20-GRGR | 20 (40 μL) | 200 μL |
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| SFN-TYK2-20-GRAQ | 20 (40 μL) | 200 μL |
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| SFN-TYK2-20-AQRE | 20 (40 μL) | 200 μL |
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| SFN-TYK2-20-AQOR | 20 (40 μL) | 200 μL |
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| SFN-TYK2-20-AQGO | 20 (40 μL) | 200 μL |
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| SFN-TYK2-20-AQGR | 20 (40 μL) | 200 μL |
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| SFN-TYK2-20-AQAQ | 20 (40 μL) | 200 μL |
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SFN Gene Summary
This gene encodes a cell cycle checkpoint protein. The encoded protein binds to translation and initiation factors and functions as a regulator of mitotic translation. In response to DNA damage this protein plays a role in preventing DNA errors during mitosis. [provided by RefSeq, Aug 2017]
Gene Name: Stratifin
Chromosome: CHR1: 27189632 -27190947
Locus: 1p36.11
TYK2 Gene Summary
This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008]
Gene Name: Tyrosine Kinase 2
Chromosome: CHR19: 10461203 -10491248
Locus: 19p13.2
Gene Diseases
The SFN TYK2 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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