SFTPB-SLC35C1 Fusion FISH Probe
The SFTPB-SLC35C1 Fusion FISH Probe is used to confirm a fusion of the SFTPB and SLC35C1 genes. The fusion of the SFTPB and SLC35C1 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SFTPB-SLC35C1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SFTPB-SLC35C1-20-RERE | 20 (40 μL) | 200 μL |
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| SFTPB-SLC35C1-20-REOR | 20 (40 μL) | 200 μL |
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| SFTPB-SLC35C1-20-REGO | 20 (40 μL) | 200 μL |
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| SFTPB-SLC35C1-20-REGR | 20 (40 μL) | 200 μL |
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| SFTPB-SLC35C1-20-REAQ | 20 (40 μL) | 200 μL |
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| SFTPB-SLC35C1-20-ORRE | 20 (40 μL) | 200 μL |
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| SFTPB-SLC35C1-20-OROR | 20 (40 μL) | 200 μL |
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| SFTPB-SLC35C1-20-ORGO | 20 (40 μL) | 200 μL |
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| SFTPB-SLC35C1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SFTPB-SLC35C1-20-GORE | 20 (40 μL) | 200 μL |
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| SFTPB-SLC35C1-20-GOOR | 20 (40 μL) | 200 μL |
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| SFTPB-SLC35C1-20-GOGO | 20 (40 μL) | 200 μL |
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| SFTPB-SLC35C1-20-GOGR | 20 (40 μL) | 200 μL |
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| SFTPB-SLC35C1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SFTPB-SLC35C1-20-GRRE | 20 (40 μL) | 200 μL |
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| SFTPB-SLC35C1-20-GROR | 20 (40 μL) | 200 μL |
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| SFTPB-SLC35C1-20-GRGO | 20 (40 μL) | 200 μL |
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| SFTPB-SLC35C1-20-GRGR | 20 (40 μL) | 200 μL |
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| SFTPB-SLC35C1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SFTPB-SLC35C1-20-AQRE | 20 (40 μL) | 200 μL |
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| SFTPB-SLC35C1-20-AQOR | 20 (40 μL) | 200 μL |
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| SFTPB-SLC35C1-20-AQGO | 20 (40 μL) | 200 μL |
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| SFTPB-SLC35C1-20-AQGR | 20 (40 μL) | 200 μL |
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| SFTPB-SLC35C1-20-AQAQ | 20 (40 μL) | 200 μL |
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SFTPB Gene Summary
This gene encodes the pulmonary-associated surfactant protein B (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. The SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 1, also called pulmonary alveolar proteinosis due to surfactant protein B deficiency, and are associated with fatal respiratory distress in the neonatal period. Alternatively spliced transcript variants encoding the same protein have been identified.[provided by RefSeq, Feb 2010]
Gene Name: Surfactant Protein B
Chromosome: CHR2: 85884439 -85895864
Locus: 2p11.2
SLC35C1 Gene Summary
This gene encodes a GDP-fucose transporter that is found in the Golgi apparatus. Mutations in this gene result in congenital disorder of glycosylation type IIc. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]
Gene Name: Solute Carrier Family 35 Member C1
Chromosome: CHR11: 45825622 -45834567
Locus: 11p11.2
Gene Diseases
The SFTPB SLC35C1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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