SH3KBP1-VSIG1 Fusion FISH Probe
The SH3KBP1-VSIG1 Fusion FISH Probe is used to confirm a fusion of the SH3KBP1 and VSIG1 genes. The fusion of the SH3KBP1 and VSIG1 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SH3KBP1-VSIG1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SH3KBP1-VSIG1-20-RERE | 20 (40 μL) | 200 μL |
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| SH3KBP1-VSIG1-20-REOR | 20 (40 μL) | 200 μL |
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| SH3KBP1-VSIG1-20-REGO | 20 (40 μL) | 200 μL |
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| SH3KBP1-VSIG1-20-REGR | 20 (40 μL) | 200 μL |
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| SH3KBP1-VSIG1-20-REAQ | 20 (40 μL) | 200 μL |
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| SH3KBP1-VSIG1-20-ORRE | 20 (40 μL) | 200 μL |
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| SH3KBP1-VSIG1-20-OROR | 20 (40 μL) | 200 μL |
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| SH3KBP1-VSIG1-20-ORGO | 20 (40 μL) | 200 μL |
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| SH3KBP1-VSIG1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SH3KBP1-VSIG1-20-GORE | 20 (40 μL) | 200 μL |
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| SH3KBP1-VSIG1-20-GOOR | 20 (40 μL) | 200 μL |
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| SH3KBP1-VSIG1-20-GOGO | 20 (40 μL) | 200 μL |
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| SH3KBP1-VSIG1-20-GOGR | 20 (40 μL) | 200 μL |
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| SH3KBP1-VSIG1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SH3KBP1-VSIG1-20-GRRE | 20 (40 μL) | 200 μL |
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| SH3KBP1-VSIG1-20-GROR | 20 (40 μL) | 200 μL |
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| SH3KBP1-VSIG1-20-GRGO | 20 (40 μL) | 200 μL |
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| SH3KBP1-VSIG1-20-GRGR | 20 (40 μL) | 200 μL |
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| SH3KBP1-VSIG1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SH3KBP1-VSIG1-20-AQRE | 20 (40 μL) | 200 μL |
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| SH3KBP1-VSIG1-20-AQOR | 20 (40 μL) | 200 μL |
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| SH3KBP1-VSIG1-20-AQGO | 20 (40 μL) | 200 μL |
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| SH3KBP1-VSIG1-20-AQGR | 20 (40 μL) | 200 μL |
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| SH3KBP1-VSIG1-20-AQAQ | 20 (40 μL) | 200 μL |
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SH3KBP1 Gene Summary
This gene encodes an adapter protein that contains one or more N-terminal Src homology domains, a proline rich region and a C-terminal coiled-coil domain. The encoded protein facilitates protein-protein interactions and has been implicated in numerous cellular processes including apoptosis, cytoskeletal rearrangement, cell adhesion and in the regulation of clathrin-dependent endocytosis. Alternate splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2017]
Gene Name: SH3 Domain Containing Kinase Binding Protein 1
Chromosome: CHRX: 19552082 -19905744
Locus: Xp22.12
VSIG1 Gene Summary
This gene encodes a member of the junctional adhesion molecule (JAM) family. The encoded protein contains multiple glycosylation sites at the N-terminal region, and multiple phosphorylation sites and glutamic acid/proline (EP) repeats at the C-terminal region. The gene is expressed in normal stomach and testis, as well as in gastric, esophageal and ovarian cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]
Gene Name: V-set And Immunoglobulin Domain Containing 1
Chromosome: CHRX: 107288199 -107322414
Locus: Xq22.3
Gene Diseases
The SH3KBP1 VSIG1 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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