SH3PXD2A-RB1 Fusion FISH Probe
The SH3PXD2A-RB1 Fusion FISH Probe is used to confirm a fusion of the SH3PXD2A and RB1 genes. The fusion of the SH3PXD2A and RB1 genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SH3PXD2A-RB1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SH3PXD2A-RB1-20-RERE | 20 (40 μL) | 200 μL |
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| SH3PXD2A-RB1-20-REOR | 20 (40 μL) | 200 μL |
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| SH3PXD2A-RB1-20-REGO | 20 (40 μL) | 200 μL |
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| SH3PXD2A-RB1-20-REGR | 20 (40 μL) | 200 μL |
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| SH3PXD2A-RB1-20-REAQ | 20 (40 μL) | 200 μL |
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| SH3PXD2A-RB1-20-ORRE | 20 (40 μL) | 200 μL |
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| SH3PXD2A-RB1-20-OROR | 20 (40 μL) | 200 μL |
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| SH3PXD2A-RB1-20-ORGO | 20 (40 μL) | 200 μL |
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| SH3PXD2A-RB1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SH3PXD2A-RB1-20-GORE | 20 (40 μL) | 200 μL |
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| SH3PXD2A-RB1-20-GOOR | 20 (40 μL) | 200 μL |
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| SH3PXD2A-RB1-20-GOGO | 20 (40 μL) | 200 μL |
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| SH3PXD2A-RB1-20-GOGR | 20 (40 μL) | 200 μL |
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| SH3PXD2A-RB1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SH3PXD2A-RB1-20-GRRE | 20 (40 μL) | 200 μL |
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| SH3PXD2A-RB1-20-GROR | 20 (40 μL) | 200 μL |
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| SH3PXD2A-RB1-20-GRGO | 20 (40 μL) | 200 μL |
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| SH3PXD2A-RB1-20-GRGR | 20 (40 μL) | 200 μL |
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| SH3PXD2A-RB1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SH3PXD2A-RB1-20-AQRE | 20 (40 μL) | 200 μL |
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| SH3PXD2A-RB1-20-AQOR | 20 (40 μL) | 200 μL |
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| SH3PXD2A-RB1-20-AQGO | 20 (40 μL) | 200 μL |
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| SH3PXD2A-RB1-20-AQGR | 20 (40 μL) | 200 μL |
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| SH3PXD2A-RB1-20-AQAQ | 20 (40 μL) | 200 μL |
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RB1 Gene Summary
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]
Gene Name: RB Transcriptional Corepressor 1
Chromosome: CHR13: 48877882 -49056026
Locus: 13q14.2
SH3PXD2A Gene Summary
The SH3 And PX Domains 2A (SH3PXD2A) gene is located on chr10 :105353783-105615164 at 10q24.33.
Gene Name: SH3 And PX Domains 2A
Chromosome: CHR10: 105353783 -105615164
Locus: 10q24.33
Gene Diseases
The SH3PXD2A RB1 Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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