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SIL1-CTNNA1 Fusion FISH Probe

The SIL1-CTNNA1 Fusion FISH Probe is used to confirm a fusion of the SIL1 and CTNNA1 genes. The fusion of the SIL1 and CTNNA1 genes has been associated with Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
SIL1-CTNNA1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
SIL1-CTNNA1-20-RERE 20 (40 μL) 200 μL
SIL1-CTNNA1-20-REOR 20 (40 μL) 200 μL
SIL1-CTNNA1-20-REGO 20 (40 μL) 200 μL
SIL1-CTNNA1-20-REGR 20 (40 μL) 200 μL
SIL1-CTNNA1-20-REAQ 20 (40 μL) 200 μL
SIL1-CTNNA1-20-ORRE 20 (40 μL) 200 μL
SIL1-CTNNA1-20-OROR 20 (40 μL) 200 μL
SIL1-CTNNA1-20-ORGO 20 (40 μL) 200 μL
SIL1-CTNNA1-20-ORAQ 20 (40 μL) 200 μL
SIL1-CTNNA1-20-GORE 20 (40 μL) 200 μL
SIL1-CTNNA1-20-GOOR 20 (40 μL) 200 μL
SIL1-CTNNA1-20-GOGO 20 (40 μL) 200 μL
SIL1-CTNNA1-20-GOGR 20 (40 μL) 200 μL
SIL1-CTNNA1-20-GOAQ 20 (40 μL) 200 μL
SIL1-CTNNA1-20-GRRE 20 (40 μL) 200 μL
SIL1-CTNNA1-20-GROR 20 (40 μL) 200 μL
SIL1-CTNNA1-20-GRGO 20 (40 μL) 200 μL
SIL1-CTNNA1-20-GRGR 20 (40 μL) 200 μL
SIL1-CTNNA1-20-GRAQ 20 (40 μL) 200 μL
SIL1-CTNNA1-20-AQRE 20 (40 μL) 200 μL
SIL1-CTNNA1-20-AQOR 20 (40 μL) 200 μL
SIL1-CTNNA1-20-AQGO 20 (40 μL) 200 μL
SIL1-CTNNA1-20-AQGR 20 (40 μL) 200 μL
SIL1-CTNNA1-20-AQAQ 20 (40 μL) 200 μL

CTNNA1 Gene Summary

This gene encodes a member of the catenin family of proteins that play an important role in cell adhesion process by connecting cadherins located on the plasma membrane to the actin filaments inside the cell. The encoded mechanosensing protein contains three vinculin homology domains and undergoes conformational changes in response to cytoskeletal tension, resulting in the reconfiguration of cadherin-actin filament connections. Certain mutations in this gene cause butterfly-shaped pigment dystrophy. [provided by RefSeq, May 2016]

Gene Name: Catenin Alpha 1

Chromosome: CHR5: 138089106 -138270723

Locus: 5q31.2

SIL1 Gene Summary

This gene encodes a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in this gene have been associated with Marinesco-Sjogren syndrome. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]

Gene Name: SIL1 Nucleotide Exchange Factor

Chromosome: CHR5: 138282409 -138534065

Locus: 5q31.2

Gene Diseases

The SIL1 CTNNA1 Fusion has been associated with the following diseases:

Disease Name
Uterine Corpus Endometrial Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.