SIL1-DNAJC18 Fusion FISH Probe
The SIL1-DNAJC18 Fusion FISH Probe is used to confirm a fusion of the SIL1 and DNAJC18 genes. The fusion of the SIL1 and DNAJC18 genes has been associated with Head And Neck Squamous Cell Carcinoma , and Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SIL1-DNAJC18-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SIL1-DNAJC18-20-RERE | 20 (40 μL) | 200 μL |
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| SIL1-DNAJC18-20-REOR | 20 (40 μL) | 200 μL |
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| SIL1-DNAJC18-20-REGO | 20 (40 μL) | 200 μL |
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| SIL1-DNAJC18-20-REGR | 20 (40 μL) | 200 μL |
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| SIL1-DNAJC18-20-REAQ | 20 (40 μL) | 200 μL |
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| SIL1-DNAJC18-20-ORRE | 20 (40 μL) | 200 μL |
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| SIL1-DNAJC18-20-OROR | 20 (40 μL) | 200 μL |
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| SIL1-DNAJC18-20-ORGO | 20 (40 μL) | 200 μL |
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| SIL1-DNAJC18-20-ORAQ | 20 (40 μL) | 200 μL |
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| SIL1-DNAJC18-20-GORE | 20 (40 μL) | 200 μL |
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| SIL1-DNAJC18-20-GOOR | 20 (40 μL) | 200 μL |
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| SIL1-DNAJC18-20-GOGO | 20 (40 μL) | 200 μL |
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| SIL1-DNAJC18-20-GOGR | 20 (40 μL) | 200 μL |
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| SIL1-DNAJC18-20-GOAQ | 20 (40 μL) | 200 μL |
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| SIL1-DNAJC18-20-GRRE | 20 (40 μL) | 200 μL |
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| SIL1-DNAJC18-20-GROR | 20 (40 μL) | 200 μL |
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| SIL1-DNAJC18-20-GRGO | 20 (40 μL) | 200 μL |
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| SIL1-DNAJC18-20-GRGR | 20 (40 μL) | 200 μL |
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| SIL1-DNAJC18-20-GRAQ | 20 (40 μL) | 200 μL |
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| SIL1-DNAJC18-20-AQRE | 20 (40 μL) | 200 μL |
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| SIL1-DNAJC18-20-AQOR | 20 (40 μL) | 200 μL |
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| SIL1-DNAJC18-20-AQGO | 20 (40 μL) | 200 μL |
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| SIL1-DNAJC18-20-AQGR | 20 (40 μL) | 200 μL |
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| SIL1-DNAJC18-20-AQAQ | 20 (40 μL) | 200 μL |
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SIL1 Gene Summary
This gene encodes a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in this gene have been associated with Marinesco-Sjogren syndrome. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]
Gene Name: SIL1 Nucleotide Exchange Factor
Chromosome: CHR5: 138282409 -138534065
Locus: 5q31.2
DNAJC18 Gene Summary
The DnaJ Heat Shock Protein Family (Hsp40) Member C18 (DNAJC18) gene is located on chr5 :138745891-138775214 at 5q31.2.
Gene Name: DnaJ Heat Shock Protein Family (Hsp40) Member C18
Chromosome: CHR5: 138745891 -138775214
Locus: 5q31.2
Gene Diseases
The SIL1 DNAJC18 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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