SIL1-SMC1B Fusion FISH Probe
The SIL1-SMC1B Fusion FISH Probe is used to confirm a fusion of the SIL1 and SMC1B genes. The fusion of the SIL1 and SMC1B genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SIL1-SMC1B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SIL1-SMC1B-20-RERE | 20 (40 μL) | 200 μL |
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| SIL1-SMC1B-20-REOR | 20 (40 μL) | 200 μL |
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| SIL1-SMC1B-20-REGO | 20 (40 μL) | 200 μL |
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| SIL1-SMC1B-20-REGR | 20 (40 μL) | 200 μL |
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| SIL1-SMC1B-20-REAQ | 20 (40 μL) | 200 μL |
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| SIL1-SMC1B-20-ORRE | 20 (40 μL) | 200 μL |
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| SIL1-SMC1B-20-OROR | 20 (40 μL) | 200 μL |
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| SIL1-SMC1B-20-ORGO | 20 (40 μL) | 200 μL |
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| SIL1-SMC1B-20-ORAQ | 20 (40 μL) | 200 μL |
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| SIL1-SMC1B-20-GORE | 20 (40 μL) | 200 μL |
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| SIL1-SMC1B-20-GOOR | 20 (40 μL) | 200 μL |
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| SIL1-SMC1B-20-GOGO | 20 (40 μL) | 200 μL |
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| SIL1-SMC1B-20-GOGR | 20 (40 μL) | 200 μL |
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| SIL1-SMC1B-20-GOAQ | 20 (40 μL) | 200 μL |
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| SIL1-SMC1B-20-GRRE | 20 (40 μL) | 200 μL |
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| SIL1-SMC1B-20-GROR | 20 (40 μL) | 200 μL |
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| SIL1-SMC1B-20-GRGO | 20 (40 μL) | 200 μL |
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| SIL1-SMC1B-20-GRGR | 20 (40 μL) | 200 μL |
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| SIL1-SMC1B-20-GRAQ | 20 (40 μL) | 200 μL |
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| SIL1-SMC1B-20-AQRE | 20 (40 μL) | 200 μL |
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| SIL1-SMC1B-20-AQOR | 20 (40 μL) | 200 μL |
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| SIL1-SMC1B-20-AQGO | 20 (40 μL) | 200 μL |
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| SIL1-SMC1B-20-AQGR | 20 (40 μL) | 200 μL |
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| SIL1-SMC1B-20-AQAQ | 20 (40 μL) | 200 μL |
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SMC1B Gene Summary
SMC1L2 belongs to a family of proteins required for chromatid cohesion and DNA recombination during meiosis and mitosis (3:Revenkova et al., 2001 [PubMed 11564881]).[supplied by OMIM, Mar 2008]
Gene Name: Structural Maintenance Of Chromosomes 1B
Chromosome: CHR22: 45739944 -45809500
Locus: 22q13.31
SIL1 Gene Summary
This gene encodes a resident endoplasmic reticulum (ER), N-linked glycoprotein with an N-terminal ER targeting sequence, 2 putative N-glycosylation sites, and a C-terminal ER retention signal. This protein functions as a nucleotide exchange factor for another unfolded protein response protein. Mutations in this gene have been associated with Marinesco-Sjogren syndrome. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]
Gene Name: SIL1 Nucleotide Exchange Factor
Chromosome: CHR5: 138282409 -138534065
Locus: 5q31.2
Gene Diseases
The SIL1 SMC1B Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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