SIRT1-CELF2 Fusion FISH Probe
The SIRT1-CELF2 Fusion FISH Probe is used to confirm a fusion of the SIRT1 and CELF2 genes. The fusion of the SIRT1 and CELF2 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SIRT1-CELF2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| SIRT1-CELF2-20-RERE | 20 (40 μL) | 200 μL |
|
|
| SIRT1-CELF2-20-REOR | 20 (40 μL) | 200 μL |
|
|
| SIRT1-CELF2-20-REGO | 20 (40 μL) | 200 μL |
|
|
| SIRT1-CELF2-20-REGR | 20 (40 μL) | 200 μL |
|
|
| SIRT1-CELF2-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| SIRT1-CELF2-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| SIRT1-CELF2-20-OROR | 20 (40 μL) | 200 μL |
|
|
| SIRT1-CELF2-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| SIRT1-CELF2-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| SIRT1-CELF2-20-GORE | 20 (40 μL) | 200 μL |
|
|
| SIRT1-CELF2-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| SIRT1-CELF2-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| SIRT1-CELF2-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| SIRT1-CELF2-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| SIRT1-CELF2-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| SIRT1-CELF2-20-GROR | 20 (40 μL) | 200 μL |
|
|
| SIRT1-CELF2-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| SIRT1-CELF2-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| SIRT1-CELF2-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| SIRT1-CELF2-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| SIRT1-CELF2-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| SIRT1-CELF2-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| SIRT1-CELF2-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| SIRT1-CELF2-20-AQAQ | 20 (40 μL) | 200 μL |
|
CELF2 Gene Summary
Members of the CELF/BRUNOL protein family contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing, and translation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: CUGBP Elav-like Family Member 2
Chromosome: CHR10: 11047258 -11378672
Locus: 10p14
SIRT1 Gene Summary
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]
Gene Name: Sirtuin 1
Chromosome: CHR10: 69644426 -69678147
Locus: 10q21.3
Gene Diseases
The SIRT1 CELF2 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|