SKAP1-HOXB9 Fusion FISH Probe
The SKAP1-HOXB9 Fusion FISH Probe is used to confirm a fusion of the SKAP1 and HOXB9 genes. The fusion of the SKAP1 and HOXB9 genes has been associated with Ovarian Serous Cystadenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SKAP1-HOXB9-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SKAP1-HOXB9-20-RERE | 20 (40 μL) | 200 μL |
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| SKAP1-HOXB9-20-REOR | 20 (40 μL) | 200 μL |
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| SKAP1-HOXB9-20-REGO | 20 (40 μL) | 200 μL |
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| SKAP1-HOXB9-20-REGR | 20 (40 μL) | 200 μL |
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| SKAP1-HOXB9-20-REAQ | 20 (40 μL) | 200 μL |
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| SKAP1-HOXB9-20-ORRE | 20 (40 μL) | 200 μL |
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| SKAP1-HOXB9-20-OROR | 20 (40 μL) | 200 μL |
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| SKAP1-HOXB9-20-ORGO | 20 (40 μL) | 200 μL |
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| SKAP1-HOXB9-20-ORAQ | 20 (40 μL) | 200 μL |
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| SKAP1-HOXB9-20-GORE | 20 (40 μL) | 200 μL |
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| SKAP1-HOXB9-20-GOOR | 20 (40 μL) | 200 μL |
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| SKAP1-HOXB9-20-GOGO | 20 (40 μL) | 200 μL |
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| SKAP1-HOXB9-20-GOGR | 20 (40 μL) | 200 μL |
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| SKAP1-HOXB9-20-GOAQ | 20 (40 μL) | 200 μL |
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| SKAP1-HOXB9-20-GRRE | 20 (40 μL) | 200 μL |
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| SKAP1-HOXB9-20-GROR | 20 (40 μL) | 200 μL |
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| SKAP1-HOXB9-20-GRGO | 20 (40 μL) | 200 μL |
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| SKAP1-HOXB9-20-GRGR | 20 (40 μL) | 200 μL |
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| SKAP1-HOXB9-20-GRAQ | 20 (40 μL) | 200 μL |
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| SKAP1-HOXB9-20-AQRE | 20 (40 μL) | 200 μL |
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| SKAP1-HOXB9-20-AQOR | 20 (40 μL) | 200 μL |
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| SKAP1-HOXB9-20-AQGO | 20 (40 μL) | 200 μL |
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| SKAP1-HOXB9-20-AQGR | 20 (40 μL) | 200 μL |
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| SKAP1-HOXB9-20-AQAQ | 20 (40 μL) | 200 μL |
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HOXB9 Gene Summary
This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of leukemia, prostate cancer and lung cancer. [provided by RefSeq, Jul 2008]
Gene Name: Homeobox B9
Chromosome: CHR17: 46698518 -46703835
Locus: 17q21.32
SKAP1 Gene Summary
This gene encodes a T cell adaptor protein, a class of intracellular molecules with modular domains capable of recruiting additional proteins but that exhibit no intrinsic enzymatic activity. The encoded protein contains a unique N-terminal region followed by a PH domain and C-terminal SH3 domain. Along with the adhesion and degranulation-promoting adaptor protein, the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins. [provided by RefSeq, Jul 2008]
Gene Name: Src Kinase Associated Phosphoprotein 1
Chromosome: CHR17: 46210801 -46507594
Locus: 17q21.32
Gene Diseases
The SKAP1 HOXB9 Fusion has been associated with the following diseases:
| Disease Name |
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| Ovarian Serous Cystadenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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