SLC11A2-PFKM Fusion FISH Probe
The SLC11A2-PFKM Fusion FISH Probe is used to confirm a fusion of the SLC11A2 and PFKM genes. The fusion of the SLC11A2 and PFKM genes has been associated with Glioblastoma Multiforme. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SLC11A2-PFKM-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| SLC11A2-PFKM-20-RERE | 20 (40 μL) | 200 μL |
|
|
| SLC11A2-PFKM-20-REOR | 20 (40 μL) | 200 μL |
|
|
| SLC11A2-PFKM-20-REGO | 20 (40 μL) | 200 μL |
|
|
| SLC11A2-PFKM-20-REGR | 20 (40 μL) | 200 μL |
|
|
| SLC11A2-PFKM-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| SLC11A2-PFKM-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| SLC11A2-PFKM-20-OROR | 20 (40 μL) | 200 μL |
|
|
| SLC11A2-PFKM-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| SLC11A2-PFKM-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| SLC11A2-PFKM-20-GORE | 20 (40 μL) | 200 μL |
|
|
| SLC11A2-PFKM-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| SLC11A2-PFKM-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| SLC11A2-PFKM-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| SLC11A2-PFKM-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| SLC11A2-PFKM-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| SLC11A2-PFKM-20-GROR | 20 (40 μL) | 200 μL |
|
|
| SLC11A2-PFKM-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| SLC11A2-PFKM-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| SLC11A2-PFKM-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| SLC11A2-PFKM-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| SLC11A2-PFKM-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| SLC11A2-PFKM-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| SLC11A2-PFKM-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| SLC11A2-PFKM-20-AQAQ | 20 (40 μL) | 200 μL |
|
SLC11A2 Gene Summary
This gene encodes a member of the solute carrier family 11 protein family. The product of this gene transports divalent metals and is involved in iron absorption. Mutations in this gene are associated with hypochromic microcytic anemia with iron overload. A related solute carrier family 11 protein gene is located on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2010]
Gene Name: Solute Carrier Family 11 Member 2
Chromosome: CHR12: 51373565 -51420199
Locus: 12q13.12
PFKM Gene Summary
Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.[provided by RefSeq, Nov 2009]
Gene Name: Phosphofructokinase, Muscle
Chromosome: CHR12: 48499655 -48540187
Locus: 12q13.11
Gene Diseases
The SLC11A2 PFKM Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Glioblastoma Multiforme |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|