SLC24A3-MACROD2 Fusion FISH Probe
The SLC24A3-MACROD2 Fusion FISH Probe is used to confirm a fusion of the SLC24A3 and MACROD2 genes. The fusion of the SLC24A3 and MACROD2 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SLC24A3-MACROD2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SLC24A3-MACROD2-20-RERE | 20 (40 μL) | 200 μL |
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| SLC24A3-MACROD2-20-REOR | 20 (40 μL) | 200 μL |
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| SLC24A3-MACROD2-20-REGO | 20 (40 μL) | 200 μL |
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| SLC24A3-MACROD2-20-REGR | 20 (40 μL) | 200 μL |
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| SLC24A3-MACROD2-20-REAQ | 20 (40 μL) | 200 μL |
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| SLC24A3-MACROD2-20-ORRE | 20 (40 μL) | 200 μL |
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| SLC24A3-MACROD2-20-OROR | 20 (40 μL) | 200 μL |
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| SLC24A3-MACROD2-20-ORGO | 20 (40 μL) | 200 μL |
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| SLC24A3-MACROD2-20-ORAQ | 20 (40 μL) | 200 μL |
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| SLC24A3-MACROD2-20-GORE | 20 (40 μL) | 200 μL |
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| SLC24A3-MACROD2-20-GOOR | 20 (40 μL) | 200 μL |
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| SLC24A3-MACROD2-20-GOGO | 20 (40 μL) | 200 μL |
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| SLC24A3-MACROD2-20-GOGR | 20 (40 μL) | 200 μL |
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| SLC24A3-MACROD2-20-GOAQ | 20 (40 μL) | 200 μL |
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| SLC24A3-MACROD2-20-GRRE | 20 (40 μL) | 200 μL |
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| SLC24A3-MACROD2-20-GROR | 20 (40 μL) | 200 μL |
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| SLC24A3-MACROD2-20-GRGO | 20 (40 μL) | 200 μL |
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| SLC24A3-MACROD2-20-GRGR | 20 (40 μL) | 200 μL |
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| SLC24A3-MACROD2-20-GRAQ | 20 (40 μL) | 200 μL |
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| SLC24A3-MACROD2-20-AQRE | 20 (40 μL) | 200 μL |
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| SLC24A3-MACROD2-20-AQOR | 20 (40 μL) | 200 μL |
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| SLC24A3-MACROD2-20-AQGO | 20 (40 μL) | 200 μL |
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| SLC24A3-MACROD2-20-AQGR | 20 (40 μL) | 200 μL |
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| SLC24A3-MACROD2-20-AQAQ | 20 (40 μL) | 200 μL |
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SLC24A3 Gene Summary
Plasma membrane sodium/calcium exchangers are an important component of intracellular calcium homeostasis and electrical conduction. Potassium-dependent sodium/calcium exchangers such as SLC24A3 are believed to transport 1 intracellular calcium and 1 potassium ion in exchange for 4 extracellular sodium ions (Kraev et al., 2001 [PubMed 11294880]).[supplied by OMIM, Mar 2008]
Gene Name: Solute Carrier Family 24 Member 3
Chromosome: CHR20: 19193289 -19703541
Locus: 20p11.23
MACROD2 Gene Summary
The protein encoded by this gene is a deacetylase involved in removing ADP-ribose from mono-ADP-ribosylated proteins. The encoded protein has been shown to translocate from the nucleus to the cytoplasm upon DNA damage. [provided by RefSeq, May 2017]
Gene Name: MACRO Domain Containing 2
Chromosome: CHR20: 13976145 -16033841
Locus: 20p12.1
Gene Diseases
The SLC24A3 MACROD2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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