SLC25A44-SEMA4A Fusion FISH Probe
The SLC25A44-SEMA4A Fusion FISH Probe is used to confirm a fusion of the SLC25A44 and SEMA4A genes. The fusion of the SLC25A44 and SEMA4A genes has been associated with Uterine Corpus Endometrial Carcinoma, and Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SLC25A44-SEMA4A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SLC25A44-SEMA4A-20-RERE | 20 (40 μL) | 200 μL |
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| SLC25A44-SEMA4A-20-REOR | 20 (40 μL) | 200 μL |
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| SLC25A44-SEMA4A-20-REGO | 20 (40 μL) | 200 μL |
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| SLC25A44-SEMA4A-20-REGR | 20 (40 μL) | 200 μL |
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| SLC25A44-SEMA4A-20-REAQ | 20 (40 μL) | 200 μL |
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| SLC25A44-SEMA4A-20-ORRE | 20 (40 μL) | 200 μL |
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| SLC25A44-SEMA4A-20-OROR | 20 (40 μL) | 200 μL |
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| SLC25A44-SEMA4A-20-ORGO | 20 (40 μL) | 200 μL |
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| SLC25A44-SEMA4A-20-ORAQ | 20 (40 μL) | 200 μL |
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| SLC25A44-SEMA4A-20-GORE | 20 (40 μL) | 200 μL |
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| SLC25A44-SEMA4A-20-GOOR | 20 (40 μL) | 200 μL |
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| SLC25A44-SEMA4A-20-GOGO | 20 (40 μL) | 200 μL |
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| SLC25A44-SEMA4A-20-GOGR | 20 (40 μL) | 200 μL |
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| SLC25A44-SEMA4A-20-GOAQ | 20 (40 μL) | 200 μL |
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| SLC25A44-SEMA4A-20-GRRE | 20 (40 μL) | 200 μL |
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| SLC25A44-SEMA4A-20-GROR | 20 (40 μL) | 200 μL |
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| SLC25A44-SEMA4A-20-GRGO | 20 (40 μL) | 200 μL |
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| SLC25A44-SEMA4A-20-GRGR | 20 (40 μL) | 200 μL |
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| SLC25A44-SEMA4A-20-GRAQ | 20 (40 μL) | 200 μL |
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| SLC25A44-SEMA4A-20-AQRE | 20 (40 μL) | 200 μL |
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| SLC25A44-SEMA4A-20-AQOR | 20 (40 μL) | 200 μL |
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| SLC25A44-SEMA4A-20-AQGO | 20 (40 μL) | 200 μL |
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| SLC25A44-SEMA4A-20-AQGR | 20 (40 μL) | 200 μL |
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| SLC25A44-SEMA4A-20-AQAQ | 20 (40 μL) | 200 μL |
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SLC25A44 Gene Summary
SLC25A44 belongs to the SLC25 family of mitochondrial carrier proteins (Haitina et al., 2006 [PubMed 16949250]).[supplied by OMIM, Mar 2008]
Gene Name: Solute Carrier Family 25 Member 44
Chromosome: CHR1: 156163729 -156182587
Locus: 1q22
SEMA4A Gene Summary
This gene encodes a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in numerous functions, including axon guidance, morphogenesis, carcinogenesis, and immunomodulation. The encoded protein is a single-pass type I membrane protein containing an immunoglobulin-like C2-type domain, a PSI domain and a sema domain. It inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. It is an activator of T-cell-mediated immunity and suppresses vascular endothelial growth factor (VEGF)-mediated endothelial cell migration and proliferation in vitro and angiogenesis in vivo. Mutations in this gene are associated with retinal degenerative diseases including retinitis pigmentosa type 35 (RP35) and cone-rod dystrophy type 10 (CORD10). Multiple alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Sep 2010]
Gene Name: Semaphorin 4A
Chromosome: CHR1: 156119734 -156147542
Locus: 1q22
Gene Diseases
The SLC25A44 SEMA4A Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Corpus Endometrial Carcinoma |
| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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