SLC29A2-RAB6A Fusion FISH Probe
The SLC29A2-RAB6A Fusion FISH Probe is used to confirm a fusion of the SLC29A2 and RAB6A genes. The fusion of the SLC29A2 and RAB6A genes has been associated with Cholangiocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SLC29A2-RAB6A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SLC29A2-RAB6A-20-RERE | 20 (40 μL) | 200 μL |
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| SLC29A2-RAB6A-20-REOR | 20 (40 μL) | 200 μL |
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| SLC29A2-RAB6A-20-REGO | 20 (40 μL) | 200 μL |
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| SLC29A2-RAB6A-20-REGR | 20 (40 μL) | 200 μL |
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| SLC29A2-RAB6A-20-REAQ | 20 (40 μL) | 200 μL |
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| SLC29A2-RAB6A-20-ORRE | 20 (40 μL) | 200 μL |
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| SLC29A2-RAB6A-20-OROR | 20 (40 μL) | 200 μL |
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| SLC29A2-RAB6A-20-ORGO | 20 (40 μL) | 200 μL |
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| SLC29A2-RAB6A-20-ORAQ | 20 (40 μL) | 200 μL |
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| SLC29A2-RAB6A-20-GORE | 20 (40 μL) | 200 μL |
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| SLC29A2-RAB6A-20-GOOR | 20 (40 μL) | 200 μL |
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| SLC29A2-RAB6A-20-GOGO | 20 (40 μL) | 200 μL |
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| SLC29A2-RAB6A-20-GOGR | 20 (40 μL) | 200 μL |
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| SLC29A2-RAB6A-20-GOAQ | 20 (40 μL) | 200 μL |
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| SLC29A2-RAB6A-20-GRRE | 20 (40 μL) | 200 μL |
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| SLC29A2-RAB6A-20-GROR | 20 (40 μL) | 200 μL |
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| SLC29A2-RAB6A-20-GRGO | 20 (40 μL) | 200 μL |
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| SLC29A2-RAB6A-20-GRGR | 20 (40 μL) | 200 μL |
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| SLC29A2-RAB6A-20-GRAQ | 20 (40 μL) | 200 μL |
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| SLC29A2-RAB6A-20-AQRE | 20 (40 μL) | 200 μL |
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| SLC29A2-RAB6A-20-AQOR | 20 (40 μL) | 200 μL |
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| SLC29A2-RAB6A-20-AQGO | 20 (40 μL) | 200 μL |
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| SLC29A2-RAB6A-20-AQGR | 20 (40 μL) | 200 μL |
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| SLC29A2-RAB6A-20-AQAQ | 20 (40 μL) | 200 μL |
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SLC29A2 Gene Summary
The uptake of nucleosides by transporters, such as SLC29A2, is essential for nucleotide synthesis by salvage pathways in cells that lack de novo biosynthetic pathways. Nucleoside transport also plays a key role in the regulation of many physiologic processes through its effect on adenosine concentration at the cell surface (Griffiths et al., 1997 [PubMed 9396714]).[supplied by OMIM, Nov 2008]
Gene Name: Solute Carrier Family 29 Member 2
Chromosome: CHR11: 66129991 -66139291
Locus: 11q13.2
RAB6A Gene Summary
This gene encodes a member of the RAB family, which belongs to the small GTPase superfamily. GTPases of the RAB family bind to various effectors to regulate the targeting and fusion of transport carriers to acceptor compartments. This protein is located at the Golgi apparatus, which regulates trafficking in both a retrograde (from early endosomes and Golgi to the endoplasmic reticulum) and an anterograde (from the Golgi to the plasma membrane) directions. Myosin II is an effector of this protein in these processes. This protein is also involved in assembly of human cytomegalovirus (HCMV) by interacting with the cellular protein Bicaudal D1, which interacts with the HCMV virion tegument protein, pp150. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011]
Gene Name: RAB6A, Member RAS Oncogene Family
Chromosome: CHR11: 73386682 -73472201
Locus: 11q13.4
Gene Diseases
The SLC29A2 RAB6A Fusion has been associated with the following diseases:
| Disease Name |
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| Cholangiocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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