SLC2A12-SGK1 Fusion FISH Probe
The SLC2A12-SGK1 Fusion FISH Probe is used to confirm a fusion of the SLC2A12 and SGK1 genes. The fusion of the SLC2A12 and SGK1 genes has been associated with Head And Neck Squamous Cell Carcinoma , and Uterine Corpus Endometrial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SLC2A12-SGK1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SLC2A12-SGK1-20-RERE | 20 (40 μL) | 200 μL |
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| SLC2A12-SGK1-20-REOR | 20 (40 μL) | 200 μL |
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| SLC2A12-SGK1-20-REGO | 20 (40 μL) | 200 μL |
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| SLC2A12-SGK1-20-REGR | 20 (40 μL) | 200 μL |
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| SLC2A12-SGK1-20-REAQ | 20 (40 μL) | 200 μL |
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| SLC2A12-SGK1-20-ORRE | 20 (40 μL) | 200 μL |
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| SLC2A12-SGK1-20-OROR | 20 (40 μL) | 200 μL |
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| SLC2A12-SGK1-20-ORGO | 20 (40 μL) | 200 μL |
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| SLC2A12-SGK1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SLC2A12-SGK1-20-GORE | 20 (40 μL) | 200 μL |
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| SLC2A12-SGK1-20-GOOR | 20 (40 μL) | 200 μL |
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| SLC2A12-SGK1-20-GOGO | 20 (40 μL) | 200 μL |
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| SLC2A12-SGK1-20-GOGR | 20 (40 μL) | 200 μL |
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| SLC2A12-SGK1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SLC2A12-SGK1-20-GRRE | 20 (40 μL) | 200 μL |
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| SLC2A12-SGK1-20-GROR | 20 (40 μL) | 200 μL |
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| SLC2A12-SGK1-20-GRGO | 20 (40 μL) | 200 μL |
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| SLC2A12-SGK1-20-GRGR | 20 (40 μL) | 200 μL |
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| SLC2A12-SGK1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SLC2A12-SGK1-20-AQRE | 20 (40 μL) | 200 μL |
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| SLC2A12-SGK1-20-AQOR | 20 (40 μL) | 200 μL |
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| SLC2A12-SGK1-20-AQGO | 20 (40 μL) | 200 μL |
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| SLC2A12-SGK1-20-AQGR | 20 (40 μL) | 200 μL |
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| SLC2A12-SGK1-20-AQAQ | 20 (40 μL) | 200 μL |
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SGK1 Gene Summary
This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jan 2009]
Gene Name: Serum/glucocorticoid Regulated Kinase 1
Chromosome: CHR6: 134490383 -134639196
Locus: 6q23.2
SLC2A12 Gene Summary
SLC2A12 belongs to a family of transporters that catalyze the uptake of sugars through facilitated diffusion (Rogers et al., 2002). This family of transporters show conservation of 12 transmembrane helices as well as functionally significant amino acid residues (Joost and Thorens, 2001 [PubMed 11780753]).[supplied by OMIM, Mar 2008]
Gene Name: Solute Carrier Family 2 Member 12
Chromosome: CHR6: 134308718 -134373789
Locus: 6q23.2
Gene Diseases
The SLC2A12 SGK1 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
| Uterine Corpus Endometrial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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