SLC39A14-IL4I1 Fusion FISH Probe
The SLC39A14-IL4I1 Fusion FISH Probe is used to confirm a fusion of the SLC39A14 and IL4I1 genes. The fusion of the SLC39A14 and IL4I1 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SLC39A14-IL4I1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SLC39A14-IL4I1-20-RERE | 20 (40 μL) | 200 μL |
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| SLC39A14-IL4I1-20-REOR | 20 (40 μL) | 200 μL |
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| SLC39A14-IL4I1-20-REGO | 20 (40 μL) | 200 μL |
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| SLC39A14-IL4I1-20-REGR | 20 (40 μL) | 200 μL |
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| SLC39A14-IL4I1-20-REAQ | 20 (40 μL) | 200 μL |
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| SLC39A14-IL4I1-20-ORRE | 20 (40 μL) | 200 μL |
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| SLC39A14-IL4I1-20-OROR | 20 (40 μL) | 200 μL |
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| SLC39A14-IL4I1-20-ORGO | 20 (40 μL) | 200 μL |
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| SLC39A14-IL4I1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SLC39A14-IL4I1-20-GORE | 20 (40 μL) | 200 μL |
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| SLC39A14-IL4I1-20-GOOR | 20 (40 μL) | 200 μL |
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| SLC39A14-IL4I1-20-GOGO | 20 (40 μL) | 200 μL |
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| SLC39A14-IL4I1-20-GOGR | 20 (40 μL) | 200 μL |
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| SLC39A14-IL4I1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SLC39A14-IL4I1-20-GRRE | 20 (40 μL) | 200 μL |
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| SLC39A14-IL4I1-20-GROR | 20 (40 μL) | 200 μL |
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| SLC39A14-IL4I1-20-GRGO | 20 (40 μL) | 200 μL |
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| SLC39A14-IL4I1-20-GRGR | 20 (40 μL) | 200 μL |
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| SLC39A14-IL4I1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SLC39A14-IL4I1-20-AQRE | 20 (40 μL) | 200 μL |
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| SLC39A14-IL4I1-20-AQOR | 20 (40 μL) | 200 μL |
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| SLC39A14-IL4I1-20-AQGO | 20 (40 μL) | 200 μL |
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| SLC39A14-IL4I1-20-AQGR | 20 (40 μL) | 200 μL |
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| SLC39A14-IL4I1-20-AQAQ | 20 (40 μL) | 200 μL |
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SLC39A14 Gene Summary
This gene encodes a member of the the SLC39A family of divalent metal transporters that mediates the cellular uptake of manganese, zinc, iron, and cadmium. The encoded protein contains eight transmembrane domains, a histidine-rich motif, and a metalloprotease motif, and is expressed on the plasma membrane and the endocytic vesicle membrane. It is an important transporter of nontransferrin-bound iron and a critical regulator of manganese homeostasis. Naturally occurring mutations in this gene are associated with neurodegeneration with brain iron accumulation and early-onset parkinsonism-dystonia with hypermanganesemia. [provided by RefSeq, May 2017]
Gene Name: Solute Carrier Family 39 Member 14
Chromosome: CHR8: 22224761 -22291640
Locus: 8p21.3
IL4I1 Gene Summary
This gene encodes a protein with limited similarity to L-amino acid oxidase which contains the conserved amino acids thought to be involved in catalysis and binding of flavin adenine dinucleotide (FAD) cofactor. The expression of this gene can be induced by interleukin 4 in B cells, however, expression of transcripts containing the first two exons of the upstream gene is found in other cell types. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Gene Name: Interleukin 4 Induced 1
Chromosome: CHR19: 50392913 -50432762
Locus: 19q13.33
Gene Diseases
The SLC39A14 IL4I1 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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