SLC39A14-XPO7 Fusion FISH Probe
The SLC39A14-XPO7 Fusion FISH Probe is used to confirm a fusion of the SLC39A14 and XPO7 genes. The fusion of the SLC39A14 and XPO7 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SLC39A14-XPO7-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-XPO7-20-RERE | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-XPO7-20-REOR | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-XPO7-20-REGO | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-XPO7-20-REGR | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-XPO7-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-XPO7-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-XPO7-20-OROR | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-XPO7-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-XPO7-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-XPO7-20-GORE | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-XPO7-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-XPO7-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-XPO7-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-XPO7-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-XPO7-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-XPO7-20-GROR | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-XPO7-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-XPO7-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-XPO7-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-XPO7-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-XPO7-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-XPO7-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-XPO7-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| SLC39A14-XPO7-20-AQAQ | 20 (40 μL) | 200 μL |
|
XPO7 Gene Summary
The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-16 is a member of the importin-beta superfamily of nuclear transport receptors.[supplied by OMIM, Jul 2002]
Gene Name: Exportin 7
Chromosome: CHR8: 21777179 -21864096
Locus: 8p21.3
SLC39A14 Gene Summary
This gene encodes a member of the the SLC39A family of divalent metal transporters that mediates the cellular uptake of manganese, zinc, iron, and cadmium. The encoded protein contains eight transmembrane domains, a histidine-rich motif, and a metalloprotease motif, and is expressed on the plasma membrane and the endocytic vesicle membrane. It is an important transporter of nontransferrin-bound iron and a critical regulator of manganese homeostasis. Naturally occurring mutations in this gene are associated with neurodegeneration with brain iron accumulation and early-onset parkinsonism-dystonia with hypermanganesemia. [provided by RefSeq, May 2017]
Gene Name: Solute Carrier Family 39 Member 14
Chromosome: CHR8: 22224761 -22291640
Locus: 8p21.3
Gene Diseases
The SLC39A14 XPO7 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|