SLC45A3-SKIL Fusion FISH Probe
The SLC45A3-SKIL Fusion FISH Probe is used to confirm a fusion of the SLC45A3 and SKIL genes. The fusion of the SLC45A3 and SKIL genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SLC45A3-SKIL-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SLC45A3-SKIL-20-RERE | 20 (40 μL) | 200 μL |
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| SLC45A3-SKIL-20-REOR | 20 (40 μL) | 200 μL |
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| SLC45A3-SKIL-20-REGO | 20 (40 μL) | 200 μL |
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| SLC45A3-SKIL-20-REGR | 20 (40 μL) | 200 μL |
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| SLC45A3-SKIL-20-REAQ | 20 (40 μL) | 200 μL |
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| SLC45A3-SKIL-20-ORRE | 20 (40 μL) | 200 μL |
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| SLC45A3-SKIL-20-OROR | 20 (40 μL) | 200 μL |
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| SLC45A3-SKIL-20-ORGO | 20 (40 μL) | 200 μL |
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| SLC45A3-SKIL-20-ORAQ | 20 (40 μL) | 200 μL |
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| SLC45A3-SKIL-20-GORE | 20 (40 μL) | 200 μL |
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| SLC45A3-SKIL-20-GOOR | 20 (40 μL) | 200 μL |
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| SLC45A3-SKIL-20-GOGO | 20 (40 μL) | 200 μL |
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| SLC45A3-SKIL-20-GOGR | 20 (40 μL) | 200 μL |
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| SLC45A3-SKIL-20-GOAQ | 20 (40 μL) | 200 μL |
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| SLC45A3-SKIL-20-GRRE | 20 (40 μL) | 200 μL |
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| SLC45A3-SKIL-20-GROR | 20 (40 μL) | 200 μL |
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| SLC45A3-SKIL-20-GRGO | 20 (40 μL) | 200 μL |
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| SLC45A3-SKIL-20-GRGR | 20 (40 μL) | 200 μL |
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| SLC45A3-SKIL-20-GRAQ | 20 (40 μL) | 200 μL |
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| SLC45A3-SKIL-20-AQRE | 20 (40 μL) | 200 μL |
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| SLC45A3-SKIL-20-AQOR | 20 (40 μL) | 200 μL |
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| SLC45A3-SKIL-20-AQGO | 20 (40 μL) | 200 μL |
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| SLC45A3-SKIL-20-AQGR | 20 (40 μL) | 200 μL |
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| SLC45A3-SKIL-20-AQAQ | 20 (40 μL) | 200 μL |
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SKIL Gene Summary
The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Gene Name: SKI Like Proto-oncogene
Chromosome: CHR3: 170075472 -170110950
Locus: 3q26.2
SLC45A3 Gene Summary
The Solute Carrier Family 45 Member 3 (SLC45A3) gene is located on chr1 :205626980-205649630 at 1q32.1.
Gene Name: Solute Carrier Family 45 Member 3
Chromosome: CHR1: 205626980 -205649630
Locus: 1q32.1
Gene Diseases
The SLC45A3 SKIL Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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