SLC9A3R1-FBXO18 Fusion FISH Probe
The SLC9A3R1-FBXO18 Fusion FISH Probe is used to confirm a fusion of the SLC9A3R1 and FBXO18 genes. The fusion of the SLC9A3R1 and FBXO18 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SLC9A3R1-FBXO18-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SLC9A3R1-FBXO18-20-RERE | 20 (40 μL) | 200 μL |
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| SLC9A3R1-FBXO18-20-REOR | 20 (40 μL) | 200 μL |
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| SLC9A3R1-FBXO18-20-REGO | 20 (40 μL) | 200 μL |
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| SLC9A3R1-FBXO18-20-REGR | 20 (40 μL) | 200 μL |
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| SLC9A3R1-FBXO18-20-REAQ | 20 (40 μL) | 200 μL |
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| SLC9A3R1-FBXO18-20-ORRE | 20 (40 μL) | 200 μL |
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| SLC9A3R1-FBXO18-20-OROR | 20 (40 μL) | 200 μL |
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| SLC9A3R1-FBXO18-20-ORGO | 20 (40 μL) | 200 μL |
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| SLC9A3R1-FBXO18-20-ORAQ | 20 (40 μL) | 200 μL |
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| SLC9A3R1-FBXO18-20-GORE | 20 (40 μL) | 200 μL |
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| SLC9A3R1-FBXO18-20-GOOR | 20 (40 μL) | 200 μL |
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| SLC9A3R1-FBXO18-20-GOGO | 20 (40 μL) | 200 μL |
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| SLC9A3R1-FBXO18-20-GOGR | 20 (40 μL) | 200 μL |
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| SLC9A3R1-FBXO18-20-GOAQ | 20 (40 μL) | 200 μL |
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| SLC9A3R1-FBXO18-20-GRRE | 20 (40 μL) | 200 μL |
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| SLC9A3R1-FBXO18-20-GROR | 20 (40 μL) | 200 μL |
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| SLC9A3R1-FBXO18-20-GRGO | 20 (40 μL) | 200 μL |
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| SLC9A3R1-FBXO18-20-GRGR | 20 (40 μL) | 200 μL |
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| SLC9A3R1-FBXO18-20-GRAQ | 20 (40 μL) | 200 μL |
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| SLC9A3R1-FBXO18-20-AQRE | 20 (40 μL) | 200 μL |
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| SLC9A3R1-FBXO18-20-AQOR | 20 (40 μL) | 200 μL |
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| SLC9A3R1-FBXO18-20-AQGO | 20 (40 μL) | 200 μL |
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| SLC9A3R1-FBXO18-20-AQGR | 20 (40 μL) | 200 μL |
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| SLC9A3R1-FBXO18-20-AQAQ | 20 (40 μL) | 200 μL |
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SLC9A3R1 Gene Summary
This gene encodes a sodium/hydrogen exchanger regulatory cofactor. The protein interacts with and regulates various proteins including the cystic fibrosis transmembrane conductance regulator and G-protein coupled receptors such as the beta2-adrenergic receptor and the parathyroid hormone 1 receptor. The protein also interacts with proteins that function as linkers between integral membrane and cytoskeletal proteins. The protein localizes to actin-rich structures including membrane ruffles, microvilli, and filopodia. Mutations in this gene result in hypophosphatemic nephrolithiasis/osteoporosis type 2, and loss of heterozygosity of this gene is implicated in breast cancer.[provided by RefSeq, Sep 2009]
Gene Name: SLC9A3 Regulator 1
Chromosome: CHR17: 72744762 -72765499
Locus: 17q25.1
FBXO18 Gene Summary
This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class. It contains an F-box motif and seven conserved helicase motifs, and has both DNA-dependent ATPase and DNA unwinding activities. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
Gene Name: F-box Protein, Helicase, 18
Chromosome: CHR10: 5932213 -5979556
Locus: 10p15.1
Gene Diseases
The SLC9A3R1 FBXO18 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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