SLCO3A1-BMPR2 Fusion FISH Probe
The SLCO3A1-BMPR2 Fusion FISH Probe is used to confirm a fusion of the SLCO3A1 and BMPR2 genes. The fusion of the SLCO3A1 and BMPR2 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SLCO3A1-BMPR2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SLCO3A1-BMPR2-20-RERE | 20 (40 μL) | 200 μL |
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| SLCO3A1-BMPR2-20-REOR | 20 (40 μL) | 200 μL |
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| SLCO3A1-BMPR2-20-REGO | 20 (40 μL) | 200 μL |
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| SLCO3A1-BMPR2-20-REGR | 20 (40 μL) | 200 μL |
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| SLCO3A1-BMPR2-20-REAQ | 20 (40 μL) | 200 μL |
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| SLCO3A1-BMPR2-20-ORRE | 20 (40 μL) | 200 μL |
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| SLCO3A1-BMPR2-20-OROR | 20 (40 μL) | 200 μL |
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| SLCO3A1-BMPR2-20-ORGO | 20 (40 μL) | 200 μL |
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| SLCO3A1-BMPR2-20-ORAQ | 20 (40 μL) | 200 μL |
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| SLCO3A1-BMPR2-20-GORE | 20 (40 μL) | 200 μL |
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| SLCO3A1-BMPR2-20-GOOR | 20 (40 μL) | 200 μL |
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| SLCO3A1-BMPR2-20-GOGO | 20 (40 μL) | 200 μL |
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| SLCO3A1-BMPR2-20-GOGR | 20 (40 μL) | 200 μL |
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| SLCO3A1-BMPR2-20-GOAQ | 20 (40 μL) | 200 μL |
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| SLCO3A1-BMPR2-20-GRRE | 20 (40 μL) | 200 μL |
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| SLCO3A1-BMPR2-20-GROR | 20 (40 μL) | 200 μL |
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| SLCO3A1-BMPR2-20-GRGO | 20 (40 μL) | 200 μL |
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| SLCO3A1-BMPR2-20-GRGR | 20 (40 μL) | 200 μL |
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| SLCO3A1-BMPR2-20-GRAQ | 20 (40 μL) | 200 μL |
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| SLCO3A1-BMPR2-20-AQRE | 20 (40 μL) | 200 μL |
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| SLCO3A1-BMPR2-20-AQOR | 20 (40 μL) | 200 μL |
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| SLCO3A1-BMPR2-20-AQGO | 20 (40 μL) | 200 μL |
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| SLCO3A1-BMPR2-20-AQGR | 20 (40 μL) | 200 μL |
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| SLCO3A1-BMPR2-20-AQAQ | 20 (40 μL) | 200 μL |
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BMPR2 Gene Summary
This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq, Jul 2008]
Gene Name: Bone Morphogenetic Protein Receptor Type 2
Chromosome: CHR2: 203241049 -203432474
Locus: 2q33.1-q33.2
SLCO3A1 Gene Summary
The Solute Carrier Organic Anion Transporter Family Member 3A1 (SLCO3A1) gene is located on chr15 :92396937-92715665 at 15q26.1.
Gene Name: Solute Carrier Organic Anion Transporter Family Member 3A1
Chromosome: CHR15: 92396937 -92715665
Locus: 15q26.1
Gene Diseases
The SLCO3A1 BMPR2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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