SLK-ZFHX3 Fusion FISH Probe
The SLK-ZFHX3 Fusion FISH Probe is used to confirm a fusion of the SLK and ZFHX3 genes. The fusion of the SLK and ZFHX3 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SLK-ZFHX3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SLK-ZFHX3-20-RERE | 20 (40 μL) | 200 μL |
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| SLK-ZFHX3-20-REOR | 20 (40 μL) | 200 μL |
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| SLK-ZFHX3-20-REGO | 20 (40 μL) | 200 μL |
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| SLK-ZFHX3-20-REGR | 20 (40 μL) | 200 μL |
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| SLK-ZFHX3-20-REAQ | 20 (40 μL) | 200 μL |
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| SLK-ZFHX3-20-ORRE | 20 (40 μL) | 200 μL |
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| SLK-ZFHX3-20-OROR | 20 (40 μL) | 200 μL |
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| SLK-ZFHX3-20-ORGO | 20 (40 μL) | 200 μL |
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| SLK-ZFHX3-20-ORAQ | 20 (40 μL) | 200 μL |
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| SLK-ZFHX3-20-GORE | 20 (40 μL) | 200 μL |
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| SLK-ZFHX3-20-GOOR | 20 (40 μL) | 200 μL |
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| SLK-ZFHX3-20-GOGO | 20 (40 μL) | 200 μL |
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| SLK-ZFHX3-20-GOGR | 20 (40 μL) | 200 μL |
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| SLK-ZFHX3-20-GOAQ | 20 (40 μL) | 200 μL |
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| SLK-ZFHX3-20-GRRE | 20 (40 μL) | 200 μL |
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| SLK-ZFHX3-20-GROR | 20 (40 μL) | 200 μL |
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| SLK-ZFHX3-20-GRGO | 20 (40 μL) | 200 μL |
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| SLK-ZFHX3-20-GRGR | 20 (40 μL) | 200 μL |
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| SLK-ZFHX3-20-GRAQ | 20 (40 μL) | 200 μL |
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| SLK-ZFHX3-20-AQRE | 20 (40 μL) | 200 μL |
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| SLK-ZFHX3-20-AQOR | 20 (40 μL) | 200 μL |
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| SLK-ZFHX3-20-AQGO | 20 (40 μL) | 200 μL |
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| SLK-ZFHX3-20-AQGR | 20 (40 μL) | 200 μL |
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| SLK-ZFHX3-20-AQAQ | 20 (40 μL) | 200 μL |
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ZFHX3 Gene Summary
This gene encodes a transcription factor with multiple homeodomains and zinc finger motifs, and regulates myogenic and neuronal differentiation. The encoded protein suppresses expression of the alpha-fetoprotein gene by binding to an AT-rich enhancer motif. The protein has also been shown to negatively regulate c-Myb, and transactivate the cell cycle inhibitor cyclin-dependent kinase inhibitor 1A (also known as p21CIP1). This gene is reported to function as a tumor suppressor in several cancers, and sequence variants of this gene are also associated with atrial fibrillation. Multiple transcript variants expressed from alternate promoters and encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
Gene Name: Zinc Finger Homeobox 3
Chromosome: CHR16: 72816785 -73092534
Locus: 16q22.2-q22.3
SLK Gene Summary
The STE20 Like Kinase (SLK) gene is located on chr10 :105727469-105787342 at 10q24.33-q25.1.
Gene Name: STE20 Like Kinase
Chromosome: CHR10: 105727469 -105787342
Locus: 10q24.33-q25.1
Gene Diseases
The SLK ZFHX3 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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