SMAD3-DLGAP4 Fusion FISH Probe
The SMAD3-DLGAP4 Fusion FISH Probe is used to confirm a fusion of the SMAD3 and DLGAP4 genes. The fusion of the SMAD3 and DLGAP4 genes has been associated with Kidney Renal Clear Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
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SMAD3-DLGAP4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL | ||
SMAD3-DLGAP4-20-RERE | 20 (40 μL) | 200 μL | ||
SMAD3-DLGAP4-20-REOR | 20 (40 μL) | 200 μL | ||
SMAD3-DLGAP4-20-REGO | 20 (40 μL) | 200 μL | ||
SMAD3-DLGAP4-20-REGR | 20 (40 μL) | 200 μL | ||
SMAD3-DLGAP4-20-REAQ | 20 (40 μL) | 200 μL | ||
SMAD3-DLGAP4-20-ORRE | 20 (40 μL) | 200 μL | ||
SMAD3-DLGAP4-20-OROR | 20 (40 μL) | 200 μL | ||
SMAD3-DLGAP4-20-ORGO | 20 (40 μL) | 200 μL | ||
SMAD3-DLGAP4-20-ORAQ | 20 (40 μL) | 200 μL | ||
SMAD3-DLGAP4-20-GORE | 20 (40 μL) | 200 μL | ||
SMAD3-DLGAP4-20-GOOR | 20 (40 μL) | 200 μL | ||
SMAD3-DLGAP4-20-GOGO | 20 (40 μL) | 200 μL | ||
SMAD3-DLGAP4-20-GOGR | 20 (40 μL) | 200 μL | ||
SMAD3-DLGAP4-20-GOAQ | 20 (40 μL) | 200 μL | ||
SMAD3-DLGAP4-20-GRRE | 20 (40 μL) | 200 μL | ||
SMAD3-DLGAP4-20-GROR | 20 (40 μL) | 200 μL | ||
SMAD3-DLGAP4-20-GRGO | 20 (40 μL) | 200 μL | ||
SMAD3-DLGAP4-20-GRGR | 20 (40 μL) | 200 μL | ||
SMAD3-DLGAP4-20-GRAQ | 20 (40 μL) | 200 μL | ||
SMAD3-DLGAP4-20-AQRE | 20 (40 μL) | 200 μL | ||
SMAD3-DLGAP4-20-AQOR | 20 (40 μL) | 200 μL | ||
SMAD3-DLGAP4-20-AQGO | 20 (40 μL) | 200 μL | ||
SMAD3-DLGAP4-20-AQGR | 20 (40 μL) | 200 μL | ||
SMAD3-DLGAP4-20-AQAQ | 20 (40 μL) | 200 μL |
SMAD3 Gene Summary
The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis. [provided by RefSeq, Apr 2009]
Gene Name: SMAD Family Member 3
Chromosome: CHR15: 67358194 -67487533
Locus: 15q22.33
DLGAP4 Gene Summary
The product of this gene is a membrane-associated guanylate kinase found at the postsynaptic density in neuronal cells. It is a signaling molecule that can interact with potassium channels and receptors, as well as other signaling molecules. The protein encoded by this gene can interact with PSD-95 through its guanylate kinase domain and may be involved in clustering PSD-95 in the postsynaptic density region. The encoded protein is one of at least four similar proteins that have been found. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Name: DLG Associated Protein 4
Chromosome: CHR20: 34995443 -35157040
Locus: 20q11.23
Gene Diseases
The SMAD3 DLGAP4 Fusion has been associated with the following diseases:
Disease Name |
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Kidney Renal Clear Cell Carcinoma |
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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