SMAD3-SMAD6 Fusion FISH Probe
The SMAD3-SMAD6 Fusion FISH Probe is used to confirm a fusion of the SMAD3 and SMAD6 genes. The fusion of the SMAD3 and SMAD6 genes has been associated with Lung Adenocarcinoma, and Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SMAD3-SMAD6-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| SMAD3-SMAD6-20-RERE | 20 (40 μL) | 200 μL |
|
|
| SMAD3-SMAD6-20-REOR | 20 (40 μL) | 200 μL |
|
|
| SMAD3-SMAD6-20-REGO | 20 (40 μL) | 200 μL |
|
|
| SMAD3-SMAD6-20-REGR | 20 (40 μL) | 200 μL |
|
|
| SMAD3-SMAD6-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| SMAD3-SMAD6-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| SMAD3-SMAD6-20-OROR | 20 (40 μL) | 200 μL |
|
|
| SMAD3-SMAD6-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| SMAD3-SMAD6-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| SMAD3-SMAD6-20-GORE | 20 (40 μL) | 200 μL |
|
|
| SMAD3-SMAD6-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| SMAD3-SMAD6-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| SMAD3-SMAD6-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| SMAD3-SMAD6-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| SMAD3-SMAD6-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| SMAD3-SMAD6-20-GROR | 20 (40 μL) | 200 μL |
|
|
| SMAD3-SMAD6-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| SMAD3-SMAD6-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| SMAD3-SMAD6-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| SMAD3-SMAD6-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| SMAD3-SMAD6-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| SMAD3-SMAD6-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| SMAD3-SMAD6-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| SMAD3-SMAD6-20-AQAQ | 20 (40 μL) | 200 μL |
|
SMAD3 Gene Summary
The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis. [provided by RefSeq, Apr 2009]
Gene Name: SMAD Family Member 3
Chromosome: CHR15: 67358194 -67487533
Locus: 15q22.33
SMAD6 Gene Summary
The protein encoded by this gene belongs to the SMAD family of proteins, which are related to Drosophila 'mothers against decapentaplegic' (Mad) and C. elegans Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions in the negative regulation of BMP and TGF-beta/activin-signalling. Multiple transcript variants have been found for this gene.[provided by RefSeq, Sep 2014]
Gene Name: SMAD Family Member 6
Chromosome: CHR15: 66994673 -67074337
Locus: 15q22.31
Gene Diseases
The SMAD3 SMAD6 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Lung Adenocarcinoma |
| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|