SMG1-SNF8 Fusion FISH Probe
The SMG1-SNF8 Fusion FISH Probe is used to confirm a fusion of the SMG1 and SNF8 genes. The fusion of the SMG1 and SNF8 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SMG1-SNF8-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SMG1-SNF8-20-RERE | 20 (40 μL) | 200 μL |
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| SMG1-SNF8-20-REOR | 20 (40 μL) | 200 μL |
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| SMG1-SNF8-20-REGO | 20 (40 μL) | 200 μL |
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| SMG1-SNF8-20-REGR | 20 (40 μL) | 200 μL |
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| SMG1-SNF8-20-REAQ | 20 (40 μL) | 200 μL |
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| SMG1-SNF8-20-ORRE | 20 (40 μL) | 200 μL |
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| SMG1-SNF8-20-OROR | 20 (40 μL) | 200 μL |
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| SMG1-SNF8-20-ORGO | 20 (40 μL) | 200 μL |
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| SMG1-SNF8-20-ORAQ | 20 (40 μL) | 200 μL |
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| SMG1-SNF8-20-GORE | 20 (40 μL) | 200 μL |
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| SMG1-SNF8-20-GOOR | 20 (40 μL) | 200 μL |
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| SMG1-SNF8-20-GOGO | 20 (40 μL) | 200 μL |
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| SMG1-SNF8-20-GOGR | 20 (40 μL) | 200 μL |
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| SMG1-SNF8-20-GOAQ | 20 (40 μL) | 200 μL |
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| SMG1-SNF8-20-GRRE | 20 (40 μL) | 200 μL |
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| SMG1-SNF8-20-GROR | 20 (40 μL) | 200 μL |
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| SMG1-SNF8-20-GRGO | 20 (40 μL) | 200 μL |
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| SMG1-SNF8-20-GRGR | 20 (40 μL) | 200 μL |
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| SMG1-SNF8-20-GRAQ | 20 (40 μL) | 200 μL |
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| SMG1-SNF8-20-AQRE | 20 (40 μL) | 200 μL |
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| SMG1-SNF8-20-AQOR | 20 (40 μL) | 200 μL |
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| SMG1-SNF8-20-AQGO | 20 (40 μL) | 200 μL |
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| SMG1-SNF8-20-AQGR | 20 (40 μL) | 200 μL |
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| SMG1-SNF8-20-AQAQ | 20 (40 μL) | 200 μL |
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SNF8 Gene Summary
The protein encoded by this gene is a component of the endosomal sorting complex required for transport II (ESCRT-II), which regulates the movement of ubiquitinylated transmembrane proteins to the lysosome for degradation. This complex also interacts with the RNA polymerase II elongation factor (ELL) to overcome the repressive effects of ELL on RNA polymerase II activity. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
Gene Name: SNF8, ESCRT-II Complex Subunit
Chromosome: CHR17: 47007458 -47022154
Locus: 17q21.32
SMG1 Gene Summary
This gene encodes a protein involved in nonsense-mediated mRNA decay (NMD) as part of the mRNA surveillance complex. The protein has kinase activity and is thought to function in NMD by phosphorylating the regulator of nonsense transcripts 1 protein. Alternatively spliced transcript variants have been described, but their full-length nature has yet to be determined. [provided by RefSeq, Mar 2013]
Gene Name: SMG1, Nonsense Mediated MRNA Decay Associated PI3K Related Kinase
Chromosome: CHR16: 18816174 -18937726
Locus: 16p12.3
Gene Diseases
The SMG1 SNF8 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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