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SMURF1-SLC26A5 Fusion FISH Probe

The SMURF1-SLC26A5 Fusion FISH Probe is used to confirm a fusion of the SMURF1 and SLC26A5 genes. The fusion of the SMURF1 and SLC26A5 genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
SMURF1-SLC26A5-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
SMURF1-SLC26A5-20-RERE 20 (40 μL) 200 μL
SMURF1-SLC26A5-20-REOR 20 (40 μL) 200 μL
SMURF1-SLC26A5-20-REGO 20 (40 μL) 200 μL
SMURF1-SLC26A5-20-REGR 20 (40 μL) 200 μL
SMURF1-SLC26A5-20-REAQ 20 (40 μL) 200 μL
SMURF1-SLC26A5-20-ORRE 20 (40 μL) 200 μL
SMURF1-SLC26A5-20-OROR 20 (40 μL) 200 μL
SMURF1-SLC26A5-20-ORGO 20 (40 μL) 200 μL
SMURF1-SLC26A5-20-ORAQ 20 (40 μL) 200 μL
SMURF1-SLC26A5-20-GORE 20 (40 μL) 200 μL
SMURF1-SLC26A5-20-GOOR 20 (40 μL) 200 μL
SMURF1-SLC26A5-20-GOGO 20 (40 μL) 200 μL
SMURF1-SLC26A5-20-GOGR 20 (40 μL) 200 μL
SMURF1-SLC26A5-20-GOAQ 20 (40 μL) 200 μL
SMURF1-SLC26A5-20-GRRE 20 (40 μL) 200 μL
SMURF1-SLC26A5-20-GROR 20 (40 μL) 200 μL
SMURF1-SLC26A5-20-GRGO 20 (40 μL) 200 μL
SMURF1-SLC26A5-20-GRGR 20 (40 μL) 200 μL
SMURF1-SLC26A5-20-GRAQ 20 (40 μL) 200 μL
SMURF1-SLC26A5-20-AQRE 20 (40 μL) 200 μL
SMURF1-SLC26A5-20-AQOR 20 (40 μL) 200 μL
SMURF1-SLC26A5-20-AQGO 20 (40 μL) 200 μL
SMURF1-SLC26A5-20-AQGR 20 (40 μL) 200 μL
SMURF1-SLC26A5-20-AQAQ 20 (40 μL) 200 μL

SMURF1 Gene Summary

This gene encodes a ubiquitin ligase that is specific for receptor-regulated SMAD proteins in the bone morphogenetic protein (BMP) pathway. This protein plays a key roll in the regulation of cell motility, cell signalling, and cell polarity. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Dec 2010]

Gene Name: SMAD Specific E3 Ubiquitin Protein Ligase 1

Chromosome: CHR7: 98625057 -98741743

Locus: 7q22.1

SLC26A5 Gene Summary

This gene encodes a member of the SLC26A/SulP transporter family. The protein functions as a molecular motor in motile outer hair cells (OHCs) of the cochlea, inducing changes in cell length that act to amplify sound levels. The transmembrane protein is an incomplete anion transporter, and does not allow anions to cross the cell membrane but instead undergoes a conformational change in response to changes in intracellular Cl- levels that results in a change in cell length. The protein functions at microsecond rates, which is several orders of magnitude faster than conventional molecular motor proteins. Mutations in this gene are potential candidates for causing neurosensory deafness. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Nov 2009]

Gene Name: Solute Carrier Family 26 Member 5

Chromosome: CHR7: 102993176 -103086624

Locus: 7q22.1

Gene Diseases

The SMURF1 SLC26A5 Fusion has been associated with the following diseases:

Disease Name
Lung Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.