SMYD3-COPA Fusion FISH Probe
The SMYD3-COPA Fusion FISH Probe is used to confirm a fusion of the SMYD3 and COPA genes. The fusion of the SMYD3 and COPA genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SMYD3-COPA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SMYD3-COPA-20-RERE | 20 (40 μL) | 200 μL |
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| SMYD3-COPA-20-REOR | 20 (40 μL) | 200 μL |
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| SMYD3-COPA-20-REGO | 20 (40 μL) | 200 μL |
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| SMYD3-COPA-20-REGR | 20 (40 μL) | 200 μL |
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| SMYD3-COPA-20-REAQ | 20 (40 μL) | 200 μL |
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| SMYD3-COPA-20-ORRE | 20 (40 μL) | 200 μL |
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| SMYD3-COPA-20-OROR | 20 (40 μL) | 200 μL |
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| SMYD3-COPA-20-ORGO | 20 (40 μL) | 200 μL |
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| SMYD3-COPA-20-ORAQ | 20 (40 μL) | 200 μL |
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| SMYD3-COPA-20-GORE | 20 (40 μL) | 200 μL |
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| SMYD3-COPA-20-GOOR | 20 (40 μL) | 200 μL |
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| SMYD3-COPA-20-GOGO | 20 (40 μL) | 200 μL |
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| SMYD3-COPA-20-GOGR | 20 (40 μL) | 200 μL |
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| SMYD3-COPA-20-GOAQ | 20 (40 μL) | 200 μL |
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| SMYD3-COPA-20-GRRE | 20 (40 μL) | 200 μL |
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| SMYD3-COPA-20-GROR | 20 (40 μL) | 200 μL |
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| SMYD3-COPA-20-GRGO | 20 (40 μL) | 200 μL |
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| SMYD3-COPA-20-GRGR | 20 (40 μL) | 200 μL |
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| SMYD3-COPA-20-GRAQ | 20 (40 μL) | 200 μL |
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| SMYD3-COPA-20-AQRE | 20 (40 μL) | 200 μL |
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| SMYD3-COPA-20-AQOR | 20 (40 μL) | 200 μL |
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| SMYD3-COPA-20-AQGO | 20 (40 μL) | 200 μL |
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| SMYD3-COPA-20-AQGR | 20 (40 μL) | 200 μL |
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| SMYD3-COPA-20-AQAQ | 20 (40 μL) | 200 μL |
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COPA Gene Summary
In eukaryotic cells, protein transport between the endoplasmic reticulum and Golgi compartments is mediated in part by non-clathrin-coated vesicular coat proteins (COPs). Seven coat proteins have been identified, and they represent subunits of a complex known as coatomer. The subunits are designated alpha-COP, beta-COP, beta-prime-COP, gamma-COP, delta-COP, epsilon-COP, and zeta-COP. The alpha-COP, encoded by COPA, shares high sequence similarity with RET1P, the alpha subunit of the coatomer complex in yeast. Also, the N-terminal 25 amino acids of alpha-COP encode the bioactive peptide, xenin, which stimulates exocrine pancreatic secretion and may act as a gastrointestinal hormone. Alternative splicing results in multiple splice forms encoding distinct isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Coatomer Protein Complex Subunit Alpha
Chromosome: CHR1: 160258376 -160313354
Locus: 1q23.2
SMYD3 Gene Summary
This gene encodes a histone methyltransferase which functions in RNA polymerase II complexes by an interaction with a specific RNA helicase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
Gene Name: SET And MYND Domain Containing 3
Chromosome: CHR1: 245912641 -246670644
Locus: 1q44
Gene Diseases
The SMYD3 COPA Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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