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SNRNP40-MAP2K5 Fusion FISH Probe

The SNRNP40-MAP2K5 Fusion FISH Probe is used to confirm a fusion of the SNRNP40 and MAP2K5 genes. The fusion of the SNRNP40 and MAP2K5 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
SNRNP40-MAP2K5-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
SNRNP40-MAP2K5-20-RERE 20 (40 μL) 200 μL
SNRNP40-MAP2K5-20-REOR 20 (40 μL) 200 μL
SNRNP40-MAP2K5-20-REGO 20 (40 μL) 200 μL
SNRNP40-MAP2K5-20-REGR 20 (40 μL) 200 μL
SNRNP40-MAP2K5-20-REAQ 20 (40 μL) 200 μL
SNRNP40-MAP2K5-20-ORRE 20 (40 μL) 200 μL
SNRNP40-MAP2K5-20-OROR 20 (40 μL) 200 μL
SNRNP40-MAP2K5-20-ORGO 20 (40 μL) 200 μL
SNRNP40-MAP2K5-20-ORAQ 20 (40 μL) 200 μL
SNRNP40-MAP2K5-20-GORE 20 (40 μL) 200 μL
SNRNP40-MAP2K5-20-GOOR 20 (40 μL) 200 μL
SNRNP40-MAP2K5-20-GOGO 20 (40 μL) 200 μL
SNRNP40-MAP2K5-20-GOGR 20 (40 μL) 200 μL
SNRNP40-MAP2K5-20-GOAQ 20 (40 μL) 200 μL
SNRNP40-MAP2K5-20-GRRE 20 (40 μL) 200 μL
SNRNP40-MAP2K5-20-GROR 20 (40 μL) 200 μL
SNRNP40-MAP2K5-20-GRGO 20 (40 μL) 200 μL
SNRNP40-MAP2K5-20-GRGR 20 (40 μL) 200 μL
SNRNP40-MAP2K5-20-GRAQ 20 (40 μL) 200 μL
SNRNP40-MAP2K5-20-AQRE 20 (40 μL) 200 μL
SNRNP40-MAP2K5-20-AQOR 20 (40 μL) 200 μL
SNRNP40-MAP2K5-20-AQGO 20 (40 μL) 200 μL
SNRNP40-MAP2K5-20-AQGR 20 (40 μL) 200 μL
SNRNP40-MAP2K5-20-AQAQ 20 (40 μL) 200 μL

MAP2K5 Gene Summary

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically interacts with and activates MAPK7/ERK5. This kinase itself can be phosphorylated and activated by MAP3K3/MEKK3, as well as by atypical protein kinase C isoforms (aPKCs). The signal cascade mediated by this kinase is involved in growth factor stimulated cell proliferation and muscle cell differentiation. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been described. [provided by RefSeq, May 2011]

Gene Name: Mitogen-activated Protein Kinase Kinase 5

Chromosome: CHR15: 67835020 -68099455

Locus: 15q23

SNRNP40 Gene Summary

This gene encodes a component of the U5 small nuclear ribonucleoprotein (snRNP) particle. The U5 snRNP is part of the spliceosome, a multiprotein complex that catalyzes the removal of introns from pre-messenger RNAs. [provided by RefSeq, Jul 2008]

Gene Name: Small Nuclear Ribonucleoprotein U5 Subunit 40

Chromosome: CHR1: 31732414 -31769644

Locus: 1p35.2

Gene Diseases

The SNRNP40 MAP2K5 Fusion has been associated with the following diseases:

Disease Name
Stomach Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.