SNX11-SNF8 Fusion FISH Probe
The SNX11-SNF8 Fusion FISH Probe is used to confirm a fusion of the SNX11 and SNF8 genes. The fusion of the SNX11 and SNF8 genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SNX11-SNF8-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| SNX11-SNF8-20-RERE | 20 (40 μL) | 200 μL |
|
|
| SNX11-SNF8-20-REOR | 20 (40 μL) | 200 μL |
|
|
| SNX11-SNF8-20-REGO | 20 (40 μL) | 200 μL |
|
|
| SNX11-SNF8-20-REGR | 20 (40 μL) | 200 μL |
|
|
| SNX11-SNF8-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| SNX11-SNF8-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| SNX11-SNF8-20-OROR | 20 (40 μL) | 200 μL |
|
|
| SNX11-SNF8-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| SNX11-SNF8-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| SNX11-SNF8-20-GORE | 20 (40 μL) | 200 μL |
|
|
| SNX11-SNF8-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| SNX11-SNF8-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| SNX11-SNF8-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| SNX11-SNF8-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| SNX11-SNF8-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| SNX11-SNF8-20-GROR | 20 (40 μL) | 200 μL |
|
|
| SNX11-SNF8-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| SNX11-SNF8-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| SNX11-SNF8-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| SNX11-SNF8-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| SNX11-SNF8-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| SNX11-SNF8-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| SNX11-SNF8-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| SNX11-SNF8-20-AQAQ | 20 (40 μL) | 200 μL |
|
SNF8 Gene Summary
The protein encoded by this gene is a component of the endosomal sorting complex required for transport II (ESCRT-II), which regulates the movement of ubiquitinylated transmembrane proteins to the lysosome for degradation. This complex also interacts with the RNA polymerase II elongation factor (ELL) to overcome the repressive effects of ELL on RNA polymerase II activity. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2015]
Gene Name: SNF8, ESCRT-II Complex Subunit
Chromosome: CHR17: 47007458 -47022154
Locus: 17q21.32
SNX11 Gene Summary
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein does not contain a coiled coil region, like some family members. This gene encodes a protein of unknown function. This gene results in two transcript variants differing in the 5' UTR, but encoding the same protein. [provided by RefSeq, Jul 2008]
Gene Name: Sorting Nexin 11
Chromosome: CHR17: 46184919 -46200105
Locus: 17q21.32
Gene Diseases
The SNX11 SNF8 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|