SNX13-GLCCI1 Fusion FISH Probe
The SNX13-GLCCI1 Fusion FISH Probe is used to confirm a fusion of the SNX13 and GLCCI1 genes. The fusion of the SNX13 and GLCCI1 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SNX13-GLCCI1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SNX13-GLCCI1-20-RERE | 20 (40 μL) | 200 μL |
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| SNX13-GLCCI1-20-REOR | 20 (40 μL) | 200 μL |
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| SNX13-GLCCI1-20-REGO | 20 (40 μL) | 200 μL |
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| SNX13-GLCCI1-20-REGR | 20 (40 μL) | 200 μL |
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| SNX13-GLCCI1-20-REAQ | 20 (40 μL) | 200 μL |
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| SNX13-GLCCI1-20-ORRE | 20 (40 μL) | 200 μL |
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| SNX13-GLCCI1-20-OROR | 20 (40 μL) | 200 μL |
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| SNX13-GLCCI1-20-ORGO | 20 (40 μL) | 200 μL |
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| SNX13-GLCCI1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SNX13-GLCCI1-20-GORE | 20 (40 μL) | 200 μL |
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| SNX13-GLCCI1-20-GOOR | 20 (40 μL) | 200 μL |
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| SNX13-GLCCI1-20-GOGO | 20 (40 μL) | 200 μL |
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| SNX13-GLCCI1-20-GOGR | 20 (40 μL) | 200 μL |
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| SNX13-GLCCI1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SNX13-GLCCI1-20-GRRE | 20 (40 μL) | 200 μL |
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| SNX13-GLCCI1-20-GROR | 20 (40 μL) | 200 μL |
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| SNX13-GLCCI1-20-GRGO | 20 (40 μL) | 200 μL |
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| SNX13-GLCCI1-20-GRGR | 20 (40 μL) | 200 μL |
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| SNX13-GLCCI1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SNX13-GLCCI1-20-AQRE | 20 (40 μL) | 200 μL |
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| SNX13-GLCCI1-20-AQOR | 20 (40 μL) | 200 μL |
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| SNX13-GLCCI1-20-AQGO | 20 (40 μL) | 200 μL |
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| SNX13-GLCCI1-20-AQGR | 20 (40 μL) | 200 μL |
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| SNX13-GLCCI1-20-AQAQ | 20 (40 μL) | 200 μL |
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SNX13 Gene Summary
This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking. [provided by RefSeq, Jul 2008]
Gene Name: Sorting Nexin 13
Chromosome: CHR7: 17830384 -17980131
Locus: 7p21.1
GLCCI1 Gene Summary
This gene encodes a protein of unknown function. Expression of this gene is induced by glucocorticoids and may be an early marker for glucocorticoid-induced apoptosis. Single nucleotide polymorphisms in this gene are associated with a decreased response to inhaled glucocorticoids in asthmatic patients. [provided by RefSeq, Feb 2012]
Gene Name: Glucocorticoid Induced 1
Chromosome: CHR7: 8008422 -8128709
Locus: 7p21.3
Gene Diseases
The SNX13 GLCCI1 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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