SOCS5-ADCY2 Fusion FISH Probe
The SOCS5-ADCY2 Fusion FISH Probe is used to confirm a fusion of the SOCS5 and ADCY2 genes. The fusion of the SOCS5 and ADCY2 genes has been associated with Pheochromocytoma And Paraganglioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SOCS5-ADCY2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SOCS5-ADCY2-20-RERE | 20 (40 μL) | 200 μL |
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| SOCS5-ADCY2-20-REOR | 20 (40 μL) | 200 μL |
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| SOCS5-ADCY2-20-REGO | 20 (40 μL) | 200 μL |
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| SOCS5-ADCY2-20-REGR | 20 (40 μL) | 200 μL |
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| SOCS5-ADCY2-20-REAQ | 20 (40 μL) | 200 μL |
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| SOCS5-ADCY2-20-ORRE | 20 (40 μL) | 200 μL |
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| SOCS5-ADCY2-20-OROR | 20 (40 μL) | 200 μL |
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| SOCS5-ADCY2-20-ORGO | 20 (40 μL) | 200 μL |
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| SOCS5-ADCY2-20-ORAQ | 20 (40 μL) | 200 μL |
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| SOCS5-ADCY2-20-GORE | 20 (40 μL) | 200 μL |
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| SOCS5-ADCY2-20-GOOR | 20 (40 μL) | 200 μL |
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| SOCS5-ADCY2-20-GOGO | 20 (40 μL) | 200 μL |
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| SOCS5-ADCY2-20-GOGR | 20 (40 μL) | 200 μL |
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| SOCS5-ADCY2-20-GOAQ | 20 (40 μL) | 200 μL |
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| SOCS5-ADCY2-20-GRRE | 20 (40 μL) | 200 μL |
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| SOCS5-ADCY2-20-GROR | 20 (40 μL) | 200 μL |
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| SOCS5-ADCY2-20-GRGO | 20 (40 μL) | 200 μL |
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| SOCS5-ADCY2-20-GRGR | 20 (40 μL) | 200 μL |
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| SOCS5-ADCY2-20-GRAQ | 20 (40 μL) | 200 μL |
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| SOCS5-ADCY2-20-AQRE | 20 (40 μL) | 200 μL |
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| SOCS5-ADCY2-20-AQOR | 20 (40 μL) | 200 μL |
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| SOCS5-ADCY2-20-AQGO | 20 (40 μL) | 200 μL |
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| SOCS5-ADCY2-20-AQGR | 20 (40 μL) | 200 μL |
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| SOCS5-ADCY2-20-AQAQ | 20 (40 μL) | 200 μL |
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ADCY2 Gene Summary
This gene encodes a member of the family of adenylate cyclases, which are membrane-associated enzymes that catalyze the formation of the secondary messenger cyclic adenosine monophosphate (cAMP). This enzyme is insensitive to Ca(2+)/calmodulin, and is stimulated by the G protein beta and gamma subunit complex. [provided by RefSeq, Jul 2008]
Gene Name: Adenylate Cyclase 2
Chromosome: CHR5: 7396342 -7830194
Locus: 5p15.31
SOCS5 Gene Summary
The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported. [provided by RefSeq, Jul 2008]
Gene Name: Suppressor Of Cytokine Signaling 5
Chromosome: CHR2: 46926098 -46989927
Locus: 2p21
Gene Diseases
The SOCS5 ADCY2 Fusion has been associated with the following diseases:
| Disease Name |
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| Pheochromocytoma And Paraganglioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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