SOX4-FOXP1 Fusion FISH Probe
The SOX4-FOXP1 Fusion FISH Probe is used to confirm a fusion of the SOX4 and FOXP1 genes. The fusion of the SOX4 and FOXP1 genes has been associated with Testicular Germ Cell Tumors. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| SOX4-FOXP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| SOX4-FOXP1-20-RERE | 20 (40 μL) | 200 μL |
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| SOX4-FOXP1-20-REOR | 20 (40 μL) | 200 μL |
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| SOX4-FOXP1-20-REGO | 20 (40 μL) | 200 μL |
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| SOX4-FOXP1-20-REGR | 20 (40 μL) | 200 μL |
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| SOX4-FOXP1-20-REAQ | 20 (40 μL) | 200 μL |
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| SOX4-FOXP1-20-ORRE | 20 (40 μL) | 200 μL |
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| SOX4-FOXP1-20-OROR | 20 (40 μL) | 200 μL |
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| SOX4-FOXP1-20-ORGO | 20 (40 μL) | 200 μL |
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| SOX4-FOXP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| SOX4-FOXP1-20-GORE | 20 (40 μL) | 200 μL |
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| SOX4-FOXP1-20-GOOR | 20 (40 μL) | 200 μL |
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| SOX4-FOXP1-20-GOGO | 20 (40 μL) | 200 μL |
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| SOX4-FOXP1-20-GOGR | 20 (40 μL) | 200 μL |
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| SOX4-FOXP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| SOX4-FOXP1-20-GRRE | 20 (40 μL) | 200 μL |
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| SOX4-FOXP1-20-GROR | 20 (40 μL) | 200 μL |
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| SOX4-FOXP1-20-GRGO | 20 (40 μL) | 200 μL |
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| SOX4-FOXP1-20-GRGR | 20 (40 μL) | 200 μL |
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| SOX4-FOXP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| SOX4-FOXP1-20-AQRE | 20 (40 μL) | 200 μL |
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| SOX4-FOXP1-20-AQOR | 20 (40 μL) | 200 μL |
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| SOX4-FOXP1-20-AQGO | 20 (40 μL) | 200 μL |
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| SOX4-FOXP1-20-AQGR | 20 (40 μL) | 200 μL |
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| SOX4-FOXP1-20-AQAQ | 20 (40 μL) | 200 μL |
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SOX4 Gene Summary
This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein. [provided by RefSeq, Jul 2008]
Gene Name: SRY-box 4
Chromosome: CHR6: 21593971 -21598849
Locus: 6p22.3
FOXP1 Gene Summary
This gene belongs to subfamily P of the forkhead box (FOX) transcription factor family. Forkhead box transcription factors play important roles in the regulation of tissue- and cell type-specific gene transcription during both development and adulthood. Forkhead box P1 protein contains both DNA-binding- and protein-protein binding-domains. This gene may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene(s). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: Forkhead Box P1
Chromosome: CHR3: 71004735 -71633140
Locus: 3p13
Gene Diseases
The SOX4 FOXP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Testicular Germ Cell Tumors |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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